Cruise Ships in South America

Most properties are fully refundable. Because flexibility matters.

Save an average of 15% on thousands of hotels with Expedia Rewards

Search over 2.9 million properties and 550 airlines worldwide

Find properties with these dates

Tonight
May 4 - May 5
Tomorrow
May 5 - May 6
Next weekend
May 10 - May 12

Featured Cruise Ships in South America

Outdoor pool, pool loungers
Grand Amazon Expedition - All Inclusive
5.0 star property
9.4 out of 10, Exceptional, (33)
"Great safe easy way to see the Amazon but don’t expect to see much wildlife Staff are excellent but do not speak in the main English Definitely recommend"
Grand Amazon Expedition - All Inclusive
Boating
Rivers & Forest Expeditions
4.0 star property
Rivers & Forest Expeditions
Terrace/patio
Jungle Experiences La Perla
3.5 star property
Jungle Experiences La Perla
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
Lobby sitting area
Jungle Experiences Zafiro
4.0 star property
Jungle Experiences Zafiro
View from property
Majestic Galapagos Cruise
2.5 star property
Majestic Galapagos Cruise
Front of property
La Pinta
2.5 star property
La Pinta
Don't see what you're looking for?
See all available properties in South America
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

South America Cruise Ships information

Number of reviews
33
Accommodation
6 Cruise Ships
Lowest Price
Highest Price

South America Hotel Reviews
Expedia verified reviews

NH Buenos Aires Tango

NH Buenos Aires Tango

5/5 Excellent
"Clean and quiet "
A verified traveller from Miami stayed at NH Buenos Aires Tango
Posted 3 days ago
NH Buenos Aires Tango

Explore a world of travel with Expedia

See our travel options