Southeastern Indiana Holidays

Book a Hotel + Flight or Car together to unlock savings

Photo by Serendipity Trip

  • Plan, book, travel with confidence

  • Better together

    Save up to Rp16.000.000 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Southeastern Indiana

Find the best Southeastern Indiana areas and neighborhoods for the activities you enjoy most. Learn more about Southeastern Indiana
The entrance to the Kentucky Science Center with a large circular structure in the foreground.

West Main Historic District

A noteworthy feature of West Main Historic District is its fantastic nightlife. While you're in town, be sure to stop and check out Frazier International History Museum and Louisville Slugger Museum.

Find hotels in West Main Historic District

Top hotels in Southeastern Indiana

Radisson Hotel Louisville North

Radisson Hotel Louisville North

3 out of 5
505 Marriott Drive Clarksville IN
Fully refundable
The price is Rp1.208.083 per night from 2 Dec to 3 Dec
Rp1.208.083
Rp1.365.133 total
2 Dec - 3 Dec
includes taxes & fees
7.2/10 Good! (3,464 reviews)
"Placed it for the incorrect night, was very quick at notifying the hotel so I could get it fixed and they didn't want to help me out or get me a reimbursement. I would understand, especially after reading the fine print, but it just doesn't make sense when I notified the hotel very quickly. Gave ..."

Reviewed on 30 Oct 2026

Radisson Hotel Louisville North
Derby Hotel & Suites

Derby Hotel & Suites

2 out of 5
505 K Marriot Dr Clarksville IN
Fully refundableReserve now, pay when you stay
The price is Rp816.615 per night from 2 Nov to 3 Nov
Rp816.615
Rp922.775 total
2 Nov - 3 Nov
includes taxes & fees
Derby Hotel & Suites
Hampton Inn New Albany Louisville West

Hampton Inn New Albany Louisville West

2.5 out of 5
411 W Spring Street New Albany IN
Fully refundableReserve now, pay when you stay
The price is Rp1.758.444 per night from 17 Nov to 18 Nov
Rp1.758.444
Rp1.987.042 total
17 Nov - 18 Nov
includes taxes & fees
8.8/10 Excellent! (941 reviews)
"Wonderfully clean and comfortable!"

Reviewed on 30 Oct 2026

Hampton Inn New Albany Louisville West
See all 1,162 properties in Southeastern Indiana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Southeastern Indiana attractions

A river with a bridge, a stadium, and modern buildings.

KFC Yum Center

8.8/10 (1,621 reviews)
Catch an event at KFC Yum Center during your trip to Louisville. Stroll along the riverfront or attend a sporting event in the area.
See properties

Frequently asked questions

How much does a Southeastern Indiana holiday package cost?
Our Southeastern Indiana holiday packages, which start from just , are an ideal way to save loads of cash. Pick and choose your preferred flights, hotels and rental cars to create a custom-built escape.
How do I get a cheap travel package to Southeastern Indiana?
If you love landing a bargain, bundle your bookings into a Southeastern Indiana holiday package. Whether you need flights, hotels, activities or rental cars, you can browse and book everything in one place. You'll have loads of choice at your fingertips too. Expedia has over 550 partner airlines and 1,000,000 hotel options throughout the world to choose from. Fly with who you want, stay wherever you like and save your hard-earned money — now that's the ideal escape!
Where should I stay in Southeastern Indiana?
You'll adore Louisville. Well-known attractions, such as Churchill Downs and Muhammad Ali Centre, will keep you entertained in this happening city.
What are the top hotels in Southeastern Indiana?
Galt House Hotel Trademark Collection by Wyndham and Radisson Hotel Louisville Jeffersonville know how to make their guests feel at home in Louisville. If you also plan to stay in Jeffersonville - Clarksville, have a look at Radisson Hotel Louisville Jeffersonville and JW Marriott Indianapolis. Both are top picks with travellers.
How far in advance should I book my Southeastern Indiana holiday?
It can be difficult to know when is the perfect time to book your Southeastern Indiana holiday. But usually the earlier you book, the more affordable the prices. In some cases, you can book your flights and hotels up to 12 months prior to your departure date. If you're thinking of a last-minute getaway, no need to fret! There are fabulous deals posted on Expedia every single day.
What does an Expedia Southeastern Indiana travel package include?
Packages include rental cars, flights and hotels, but you can mix and match them to create your perfect Southeastern Indiana holiday. You can also add on fun things like experiences and activities once you've made your booking. You're in the driver's seat! When you bundle your bookings with Expedia, you'll get access to deals you won't find anywhere else.
What should I know before booking a Southeastern Indiana travel package?
Whether it's adventure or relaxation you're craving, a Southeastern Indiana holiday package lets you organise your escape your way. Plus, you'll get access to great discounts just for combining your hotel with your rental car and flights. The more you bundle, the bigger the savings!
Can I choose my airline with a Southeastern Indiana Expedia holiday package?
Expedia has access to more than 550 partner airlines globally, so you definitely can. Just select your preferred carrier and craft your ideal Southeastern Indiana escape.
If I'm not able to travel, can I cancel my Southeastern Indiana holiday package?
Whether it's your hotel, flight or rental car, you can cancel or alter it. Booked your Southeastern Indiana holiday package in the last 24 hours? You may be able to make changes at no cost. For bookings made more than 24 hours ago, you may be charged a fee by your airline, hotel or car rental company. For further information, look up our Customer Service Portal. We'll help you each step of the way.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.