Southern Illinois showing a river or creek and landscape views

Search Aparthotels in Southwest Illinois

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

In two weeks

In two months

In three months

In four months

Our top choices for Southwest Illinois aparthotels

Studio Suite, 1 King Bed | Desk, laptop workspace, blackout curtains, WiFi

Value Suites Extended Stay - St Louis

Maryland Heights

Timothy

Rp8.786.471 total

includes taxes & fees

6 Jan - 7 Jan

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Top Southwest Illinois Hotel Reviews

La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis

10/10 Excellent

"Staff was Amazing upon check-in. So grateful they allowed cash deposit, especially after my card was stolen. I stopped by another hotel I've stayed at previously and was not willing to work with me. They were very adamant about having a card on file for deposit 🙄. I would most definitely stay at this location in the future. "