Cheap Flights from Medellín (MDE) to San Francisco (SFO)

Round-trip flights from Medellin Airport to SFO start from . This price is based on fares quoted within the last 7 days on Expedia for flights departing within the next year — book now to avoid missing out. Prices and availability are subject to change. Additional terms apply.

Each air carrier has its own set of terms and conditions. If you do decide to cancel, follow the simple instructions on our Customer Service Portal.

Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for Jose Maria Cordova Intl. Airport (MDE) to San Francisco Airport flights, you'll see a "no change fees" filter for you to select.

Rionegro to San Francisco is around 5,900 kilometres, so be prepared to spend a while in the air. Make sure you pack all the essentials, from your earplugs to your eye mask. Throw in a few snacks to nibble on throughout your journey too.

There are no direct flights, so you'll have to make at least one stop between MDE and SFO. Use the layover time to stretch your legs and take a break.

Flight prices always go up and down, so not always. While last-minute deals between Medellin Airport and SFO are possible, it's also a good idea to keep track of prices well before you fly. In fact, some airlines publish their prices up to 12 months ahead of the departure date. Expedia is constantly updating the best bargains around, so keep checking back and be ready to secure your seat when the fares dip.