Medical Center District Hotel Guide - 4 Stars Hotels in Medical Center District, San Antonio

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Check availability on Medical Center District 4 Star Hotels

Tonight
6 May - 7 May
Tomorrow
7 May - 8 May
This weekend
8 May - 10 May
Next weekend
15 May - 17 May

Our top choices for Medical Center District 4-star hotels

Games room

Riverwalk Plaza

Riverwalk Plaza
4.0 star property
Downtown San Antonio
8.0 out of 10, Very good, (6,448 reviews)
"Great stay overall… convenient and comfortable."
United States
Ray
The price is Rp1.411.340
Rp1.668.330 total
includes taxes & fees
12 May - 13 May
Riverwalk Plaza
Outdoor pool, a heated pool, open 8:00 AM to 10:00 PM, free pool cabanas

Hotel Contessa

Hotel Contessa
4.0 star property
Downtown San Antonio
9.0 out of 10, Wonderful, (3,553 reviews)
"Great Stay, easy the hot spots downtown and right on the riverwalk."
United States
Abram
The price is Rp2.230.969
Rp3.116.890 total
includes taxes & fees
4 Jun - 5 Jun
Hotel Contessa
3 outdoor pools, pool cabanas (surcharge), pool loungers

Hyatt Regency Hill Country Resort and Villas

Hyatt Regency Hill Country Resort and Villas
4.0 star property
Far West Side
8.8 out of 10, Excellent, (1,003 reviews)
"It was a beautiful place, cant wait to go back "
United States
Melissa
The price is Rp5.909.350
Rp8.349.983 total
includes taxes & fees
18 May - 19 May
Hyatt Regency Hill Country Resort and Villas
Outdoor pool

Kimpton Santo San Antonio - Riverwalk by IHG

Kimpton Santo San Antonio - Riverwalk by IHG
4.5 star property
Downtown San Antonio
9.4 out of 10, Exceptional, (904 reviews)
"Great stay! Super clean, wonderful staff!"
United States
Robert
The price is Rp2.944.656
Rp3.932.074 total
includes taxes & fees
17 May - 18 May
Kimpton Santo San Antonio - Riverwalk by IHG
Exterior

Hotel Valencia Riverwalk

Hotel Valencia Riverwalk
4.5 star property
Downtown San Antonio
9.4 out of 10, Exceptional, (2,719 reviews)
"Excellent hotel, excellent breakfast choices and very clean."
United States
Sherri
The price is Rp2.218.946
Rp3.120.813 total
includes taxes & fees
20 May - 21 May
Hotel Valencia Riverwalk
Deluxe Room, 2 Queen Beds | View from room

Omni La Mansion del Rio

Omni La Mansion del Rio
4.0 star property
Downtown San Antonio
9.4 out of 10, Exceptional, (2,926 reviews)
"Good stay, great location."
United States
Tammy
The price is Rp3.641.790
Rp4.369.497 total
includes taxes & fees
1 Jun - 2 Jun
Omni La Mansion del Rio
Terrace/patio

Hyatt Regency San Antonio Riverwalk

Hyatt Regency San Antonio Riverwalk
4.0 star property
Downtown San Antonio
9.2 out of 10, Wonderful, (2,137 reviews)
"Beautiful stay. "
United States
Cassandra
The price is Rp3.293.136
Rp4.453.662 total
includes taxes & fees
30 May - 31 May
Hyatt Regency San Antonio Riverwalk
Outdoor pool, open 9:00 AM to 10:00 PM, pool cabanas (surcharge)

Plaza San Antonio Hotel & Spa, Autograph Collection

Plaza San Antonio Hotel & Spa, Autograph Collection
4.0 star property
Downtown San Antonio
9.4 out of 10, Exceptional, (797 reviews)
"Great place!"
United States
Elham
The price is Rp2.117.887
Rp3.042.553 total
includes taxes & fees
31 May - 1 Jun
Plaza San Antonio Hotel & Spa, Autograph Collection
Lobby lounge

Hilton Palacio Del Rio

Hilton Palacio Del Rio
4.0 star property
Downtown San Antonio
9.0 out of 10, Wonderful, (1,173 reviews)
"Enjoyed the stay "
United States
HOMA
The price is Rp3.095.374
Rp3.659.040 total
includes taxes & fees
31 May - 1 Jun
Hilton Palacio Del Rio
4 outdoor pools, pool cabanas (surcharge), pool umbrellas

JW Marriott San Antonio Hill Country Resort & Spa

JW Marriott San Antonio Hill Country Resort & Spa
4.5 star property
San Antonio
9.0 out of 10, Wonderful, (1,005 reviews)
"Very family friendly!"
United States
Craig
The price is Rp6.603.696
Rp8.999.496 total
includes taxes & fees
26 May - 27 May
JW Marriott San Antonio Hill Country Resort & Spa
Exterior

Signia by Hilton La Cantera Resort & Spa

Signia by Hilton La Cantera Resort & Spa
4.0 star property
La Cantera District
9.0 out of 10, Wonderful, (1,038 reviews)
"Clean room and friendly staff. Everyone on the property always has a big smile!"
United States
Richie
The price is Rp4.906.598
Rp6.916.047 total
includes taxes & fees
21 May - 22 May
Signia by Hilton La Cantera Resort & Spa
Indoor pool, outdoor pool

The Westin San Antonio North

The Westin San Antonio North
4.0 star property
Vance Jackson
8.6 out of 10, Excellent, (1,367 reviews)
"A wonderful and beautiful place to stay "
United States
Uriel
The price is Rp1.794.672
Rp2.150.387 total
includes taxes & fees
24 May - 25 May
The Westin San Antonio North
Exterior

Grand Hyatt San Antonio River Walk

Grand Hyatt San Antonio River Walk
4.0 star property
Downtown San Antonio
9.2 out of 10, Wonderful, (1,377 reviews)
"Loved my room and enjoyed my stay"
United States
Esmeralda
The price is Rp3.223.440
Rp4.371.276 total
includes taxes & fees
31 May - 1 Jun
Grand Hyatt San Antonio River Walk
Exterior

InterContinental San Antonio Riverwalk by IHG

InterContinental San Antonio Riverwalk by IHG
4.5 star property
Downtown San Antonio
9.2 out of 10, Wonderful, (678 reviews)
"Great place to stay."
United States
Edward
The price is Rp2.944.656
Rp4.203.770 total
includes taxes & fees
10 May - 11 May
InterContinental San Antonio Riverwalk by IHG
2 restaurants, breakfast served

Mokara Hotel & Spa San Antonio

Mokara Hotel & Spa San Antonio
4.5 star property
Downtown San Antonio
9.6 out of 10, Exceptional, (1,001 reviews)
"Great property"
United States
Jimmy
The price is Rp5.384.190
Rp6.380.331 total
includes taxes & fees
7 May - 8 May
Mokara Hotel & Spa San Antonio
Restaurant

Canopy by Hilton San Antonio Riverwalk

Canopy by Hilton San Antonio Riverwalk
4.0 star property
Downtown San Antonio
9.4 out of 10, Exceptional, (1,678 reviews)
"Nice place to stay"
United States
Ivan
The price is Rp2.577.010
Rp3.516.707 total
includes taxes & fees
17 May - 18 May
Canopy by Hilton San Antonio Riverwalk
Exterior

Hilton San Antonio Hill Country

Hilton San Antonio Hill Country
4.0 star property
Far West Side
8.6 out of 10, Excellent, (1,104 reviews)
"nice hotel"
United States
Zeeshan
The price is Rp2.058.646
Rp3.121.510 total
includes taxes & fees
20 May - 21 May
Hilton San Antonio Hill Country
Lobby

Aiden San Antonio Riverwalk

Aiden San Antonio Riverwalk
4.0 star property
Downtown San Antonio
9.2 out of 10, Wonderful, (1,260 reviews)
"The staff was very friendly and helpful. Definitely going to stay there in the future."
United States
Miriam
The price is Rp1.398.276
Rp1.632.487 total
includes taxes & fees
10 May - 11 May
Aiden San Antonio Riverwalk
Breakfast, lunch, dinner served; Italian cuisine

The Westin Riverwalk, San Antonio

The Westin Riverwalk, San Antonio
4.0 star property
Downtown San Antonio
8.8 out of 10, Excellent, (1,533 reviews)
"Beautiful hotel"
United States
CHRISTINA
The price is Rp3.095.374
Rp3.686.366 total
includes taxes & fees
31 May - 1 Jun
The Westin Riverwalk, San Antonio
Lobby

Bluegreen Vacations Eilan Hotel and Spa, an Ascend Collection Resort

Bluegreen Vacations Eilan Hotel and Spa, an Ascend Collection Resort
4.5 star property
La Cantera District
8.4 out of 10, Very good, (1,006 reviews)
"Great location, very clean and nice facilities "
United States
Jose
The price is Rp2.421.936
Rp3.376.955 total
includes taxes & fees
10 May - 11 May
Bluegreen Vacations Eilan Hotel and Spa, an Ascend Collection Resort
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Medical Center District.
Thompson San Antonio - Riverwalk, by Hyatt

Thompson San Antonio - Riverwalk, by Hyatt

115 Lexington Avenue San Antonio TX
The price is Rp3.687.790 per night from 10 May to 11 May
Rp3.687.790
Rp4.952.148 total
10 May - 11 May
includes taxes & fees
9/10 Wonderful! (987 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Medical Center District Hotel Reviews

Omni La Mansion del Rio

Omni La Mansion del Rio

6/10 Okay
"Room service didn’t know if they can get us hot water and have to wait on hold. When calling to find out if there was an event going on in the restaurant for Brothers for Cinco de Mayo, no one knew what was going on and we ended up finding out. It was a private event. Location is great in relationship to the Riverwalk and will probably go back again. The valet were very awesome and personable. The Front Desk was very attentive every time we walked by they said hi and got us whatever we wanted"
Donald 3-night trip
Posted 1 hour ago
Omni La Mansion del Rio

Frequently asked questions

What are the best 4-star hotels in Medical Centre District?
When you plan your visit to The Westin San Antonio North, you can count on excellent service, comfortable bedding and plenty of handy amenities. This 4-star hotel located conveniently around Medical Centre District consistently receives top marks from our guests.
How much does it cost to stay in a 4-star hotel in Medical Centre District?
Expedia can help you quickly track down the ideal 4-star hotel for your holiday in Medical Centre District. Use our handy filter tool to tailor your search by things like budget, amenities and star rating and get access to awesome deals in a few clicks.

  • Search for the lowest price from Rp4.952.148

What's the difference between 5-star and 4-star hotels in Medical Centre District?
Offering a friendly traveller experience and upmarket surroundings, 4-star hotels are an excellent option for your Medical Centre District break. These types of stays generally feature lots of handy amenities that make it easy to unpack and unwind — think large beds, bathrobes, pools and restaurants. Or live the high life at a 5-star hotel designed to spoil you with luxury perks and amenities. On-site health clubs, complimentary toiletries and gourmet dining are typically included at these deluxe properties.