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4 Sept - 6 Sept
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11 Sept - 13 Sept

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Our top choices for Mayo Clinic hotels

A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.

1. Sonesta Select Scottsdale at Mayo Clinic Campus

Sonesta Select Scottsdale at Mayo Clinic Campus
3.0 star property
Mayo Clinic
8.4 out of 10, Very good, (1,103 reviews)
"Clean room friendly staff breakfast all super!"
United States
Teri
The price is Rp1.295.312
Rp1.476.266 total
includes taxes & fees
5 Sept - 6 Sept
Sonesta Select Scottsdale at Mayo Clinic Campus
A modern breakfast area with a sign reading "EXPRESS START BREAKFAST" and a "GOOD MORNING" sign on the wall.

2. Holiday Inn Express & Suites Phoenix - Airport North by IHG

Holiday Inn Express & Suites Phoenix - Airport North by IHG
2.5 star property
23.2 km from Mayo Clinic
9.4 out of 10, Exceptional, (2,416 reviews)
"Wonderful and easy stay."
United States
Robert
The price is Rp1.669.722
Rp1.887.954 total
includes taxes & fees
6 Sept - 7 Sept
Holiday Inn Express & Suites Phoenix - Airport North by IHG
A spacious lobby with a high ceiling, modern lighting, and a central seating area with sofas and a coffee table.

3. Hampton Inn & Suites Tempe/Phoenix Airport, AZ

Hampton Inn & Suites Tempe/Phoenix Airport, AZ
2.5 star property
25.4 km from Mayo Clinic
9.4 out of 10, Exceptional, (1,054 reviews)
"Perfect stay"
United States
Brian
The price is Rp1.308.591
Rp1.492.710 total
includes taxes & fees
7 Sept - 8 Sept
Hampton Inn & Suites Tempe/Phoenix Airport, AZ
A spacious dining area with multiple tables and chairs, large windows, and a television mounted on the wall.

4. Comfort Suites Scottsdale Talking Stick Entertainment District

Comfort Suites Scottsdale Talking Stick Entertainment District
2.5 star property
9.7 km from Mayo Clinic
9.2 out of 10, Wonderful, (2,005 reviews)
"The staff is extremely friendly and the breakfast amazing."
United States
Brenda
The price is Rp1.399.114
Rp1.595.269 total
includes taxes & fees
6 Sept - 7 Sept
Comfort Suites Scottsdale Talking Stick Entertainment District
A cluster of modern, multi-story buildings with a river in the foreground.

5. Inn at Eagle Mountain

Inn at Eagle Mountain
3.5 star property
3 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,009 reviews)
"Private, cozy, clean. Nice couples weekend. Lived king bed and jetted in bathroom tub. Would recommend."
United States
Monica
The price is Rp1.988.865
Rp2.270.687 total
includes taxes & fees
7 Sept - 8 Sept
Inn at Eagle Mountain
A swimming pool with lounge chairs and a covered seating area, surrounded by palm trees and a building with multiple windows.

6. Hyatt Place Phoenix/Mesa

Hyatt Place Phoenix/Mesa
3.0 star property
17.9 km from Mayo Clinic
9.2 out of 10, Wonderful, (1,978 reviews)
"Highly recommended nice clean place to stay"
United States
greg
The price is Rp1.493.158
Rp1.706.231 total
includes taxes & fees
6 Sept - 7 Sept
Hyatt Place Phoenix/Mesa
A hotel room with a bed, desk, chair, and a window with curtains.

7. Country Inn & Suites by Radisson, Phoenix Airport, AZ

Country Inn & Suites by Radisson, Phoenix Airport, AZ
3.0 star property
25.2 km from Mayo Clinic
8.4 out of 10, Very good, (3,089 reviews)
"Nice room with everything you need... and very friendly staff!"
United States
Christian
The price is Rp1.257.088
Rp1.421.390 total
includes taxes & fees
4 Sept - 5 Sept
Country Inn & Suites by Radisson, Phoenix Airport, AZ
A hotel reception area with a 'SureStay Hotel' sign, a seating area with black chairs, a wooden coffee table, and a marble wall.

8. SureStay By Best Western Phoenix Airport

SureStay By Best Western Phoenix Airport
2.5 star property
25.5 km from Mayo Clinic
8.4 out of 10, Very good, (2,460 reviews)
"Very clean and staff was friendly, felt safe"
United States
Sehar
The price is Rp1.330.800
Rp1.504.735 total
includes taxes & fees
8 Sept - 9 Sept
SureStay By Best Western Phoenix Airport
A spacious lobby with a reception desk, seating area, and a large window providing natural light.

9. Drury Inn & Suites Phoenix Airport

Drury Inn & Suites Phoenix Airport
4.0 star property
27.7 km from Mayo Clinic
9.6 out of 10, Exceptional, (2,665 reviews)
"Would definitely stay here again"
United States
Robert
The price is Rp2.004.895
Rp2.266.934 total
includes taxes & fees
7 Sept - 8 Sept
Drury Inn & Suites Phoenix Airport
A modern infinity pool with a view of mountains and a sunset.

10. Talking Stick Resort

Talking Stick Resort
4.0 star property
9 km from Mayo Clinic
9.4 out of 10, Exceptional, (5,081 reviews)
"Great stay every time!"
United States
Douglas
The price is Rp2.353.032
Rp3.188.774 total
includes taxes & fees
7 Sept - 8 Sept
Talking Stick Resort
A hotel lobby with a reception desk, seating area, and a large wall mural.

11. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale
3.0 star property
Central Scottsdale, 9 km from Mayo Clinic
8.8 out of 10, Excellent, (1,859 reviews)
"Wonderful stay."
United States
Caroline
The price is Rp1.181.750
Rp1.346.841 total
includes taxes & fees
6 Sept - 7 Sept
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale
A hotel room with a bed, a TV, a desk, and a seating area.

12. Holiday Inn Express Hotel & Suites Phoenix-Airport by IHG

Holiday Inn Express Hotel & Suites Phoenix-Airport by IHG
2.5 star property
27.5 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,897 reviews)
"Nice staff and close to airport"
United States
Brandon
The price is Rp1.543.728
Rp1.745.492 total
includes taxes & fees
6 Sept - 7 Sept
Holiday Inn Express Hotel & Suites Phoenix-Airport by IHG
An outdoor dining area with tables set for a meal, surrounded by chairs and illuminated by lanterns.

13. Radisson Hotel Phoenix Airport

Radisson Hotel Phoenix Airport
3.5 star property
23.3 km from Mayo Clinic
8.6 out of 10, Excellent, (2,051 reviews)
"Clean room, pool area was very nice, easy transportation airport!"
United States
Melissa
The price is Rp1.598.557
Rp1.807.226 total
includes taxes & fees
6 Sept - 7 Sept
Radisson Hotel Phoenix Airport
A conference room with a long table, multiple chairs, a bar area with a television, and a kitchenette.

14. Hilton Garden Inn Phoenix Airport North

Hilton Garden Inn Phoenix Airport North
3.0 star property
24.2 km from Mayo Clinic
8.8 out of 10, Excellent, (2,826 reviews)
"Love staying here"
United States
Nicholas
The price is Rp1.662.968
Rp1.880.318 total
includes taxes & fees
20 Sept - 21 Sept
Hilton Garden Inn Phoenix Airport North
A spacious dining area with multiple tables and chairs, a central counter, and a view of the outdoors through large windows.

15. Days Inn & Suites by Wyndham Mesa Near Phoenix

Days Inn & Suites by Wyndham Mesa Near Phoenix
3.0 star property
23 km from Mayo Clinic
9.0 out of 10, Wonderful, (2,479 reviews)
"Clean room, friendly staff"
United States
Gerald
The price is Rp1.266.922
Rp1.447.712 total
includes taxes & fees
8 Sept - 9 Sept
Days Inn & Suites by Wyndham Mesa Near Phoenix
A spacious hotel lobby with multiple seating areas, including sofas, chairs, and tables. There are plants and a coffee bar.

16. Embassy Suites by Hilton Phoenix Downtown North

Embassy Suites by Hilton Phoenix Downtown North
3.5 star property
28.5 km from Mayo Clinic
9.2 out of 10, Wonderful, (1,474 reviews)
"Was a great stay!"
United States
Monica
The price is Rp1.876.960
Rp2.122.279 total
includes taxes & fees
10 Sept - 11 Sept
Embassy Suites by Hilton Phoenix Downtown North
A hotel lobby with a reception desk, seating area, and large windows.

17. The Azure Hotel

The Azure Hotel
2.5 star property
19.2 km from Mayo Clinic
8.8 out of 10, Excellent, (1,913 reviews)
"Clean rooms, comfy beds, cold AC, helpful staff and convenient location."
United States
Betisha
The price is Rp731.940
Rp925.108 total
includes taxes & fees
6 Sept - 7 Sept
The Azure Hotel
A modern hotel room with a large bed, a desk, and a TV.

18. Wyndham Phoenix Airport/Tempe

Wyndham Phoenix Airport/Tempe
3.5 star property
25.5 km from Mayo Clinic
7.6 out of 10, Good, (1,803 reviews)
"Great place to stay for a few days."
United States
Yesenia Leticia
The price is Rp1.405.325
Rp1.603.054 total
includes taxes & fees
13 Sept - 14 Sept
Wyndham Phoenix Airport/Tempe
A home gym with a treadmill, elliptical, and stationary bike, large windows, and a flat-screen TV.

19. City Express by Marriott Tempe

City Express by Marriott Tempe
3.0 star property
20.6 km from Mayo Clinic
8.4 out of 10, Very good, (1,205 reviews)
"Great hotel for a quick stay!"
United States
River
The price is Rp1.490.496
Rp1.700.230 total
includes taxes & fees
6 Sept - 7 Sept
City Express by Marriott Tempe
A modern hotel room with a grey sofa, a round table, a bed with white linens, a large abstract painting, a floor lamp, and a window with curtains.

20. Hyatt Place Tempe Phoenix Airport

Hyatt Place Tempe Phoenix Airport
3.0 star property
23.5 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,166 reviews)
"Great stay. Clean room and parking was safe and convenient. The complimentary breakfast was very delightful"
United States
Naomi
The price is Rp1.433.715
Rp1.635.439 total
includes taxes & fees
4 Sept - 5 Sept
Hyatt Place Tempe Phoenix Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Mayo Clinic

Find the best Mayo Clinic areas for the activities you enjoy most.
A cityscape at dusk with illuminated buildings, including a Chase bank and a Sheraton hotel.

Downtown Phoenix

Cheer on the Phoenix Suns at an NBA game or walk around the city’s historic precinct as you explore the state capital.

A sculpture of a horse in motion, surrounded by cacti and palm trees, with buildings and a street in the background.

Old Town

Gourmet restaurants interesting history and top sights from Scottsdale Waterfront to Scottsdale Center for the Performing Arts – discover Old Town, a destination also famous for its shopping.

A hiker on a rocky trail with mountains in the background.

Rio Verde Foothills

If you're looking for some top things to see and do in Rio Verde Foothills and surrounding area, you can visit Tom's Thumb Trail and Tonto Verde Golf Club.

A cave with a view of palm trees and a distant cityscape.

Camelback East

You might take some time to check out the abundant dining options in Camelback East. Spend some time visiting top spots like Biltmore Fashion Park, and catch the metro at 44th Street - Washington Station or 50th Street Station to see more of the area.

A desert landscape with various cacti and sparse trees.

Central Scottsdale

If you're spending some time in Central Scottsdale, Scottsdale Ranch Park and Starfire Golf Club at Scottsdale Country Club are top sights worth seeing.

Top Mayo Clinic Hotel Reviews

Residence Inn by Marriott Phoenix Airport

Residence Inn by Marriott Phoenix Airport

8/10 Good
"We almost always stay here when we are flying out of Skyharbor. Very convenient to the airport, a hotel shuttle would be an improvement"
Melanie 1-night trip
Posted 4 hours ago
Residence Inn by Marriott Phoenix Airport

Frequently asked questions

What is Mayo Clinic like?
Travellers will be sure to find plenty to entertain them in Scottsdale's Mayo Clinic neighbourhood.
Where is the best place to stay in Mayo Clinic?
Based on Expedia customer reviews, Sonesta Select Scottsdale at Mayo Clinic Campus is the highest ranked property in Mayo Clinic. This hotel offers a restaurant and an outdoor pool.
How many hotels should I expect to find in the Mayo Clinic area?
With 14 Expedia hotels and other accommodation options in Mayo Clinic to choose from, this is a good starting point for exploring the greater Scottsdale area.
If I need to cancel my hotel reservation in Mayo Clinic, will I receive a refund?
Yes! Most hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a non-refundable reservation, you may still be able to cancel and be given a refund within a 24-hour period of booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best options available in Mayo Clinic.
What is there to do around this Scottsdale neighbourhood?
A few places to visit in the area around Mayo Clinic include Eagle Mountain Golf Course, Golf Club at Eagle Mountain and SunRidge Canyon Golf Club. Make a stop at Talking Stick Resort Casino and Talking Stick Golf Club while you're sightseeing around the area.