San Francisco Travel Guide

Panama City

Photo by Hideki Yamagata
Photo by ‎James Barrow
Photo by Adrian Damian
Photo by Nóra Széll
Photo by Panama Roadrunner

Popular places to visit

Things to do


Top hotels in San Francisco

Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa Panama City
Stay at this luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in their reviews. ...
8.4/10 Very Good! (1,351 reviews)
El hotel nos brindó una excelente atención.

Reviewed on 4 Jan 2026

Megapolis Hotel Panamá
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
The price is Rp2.530.385 per night from 30 Jan to 31 Jan
Rp2.530.385
Rp2.783.423 total
30 Jan - 31 Jan
includes taxes & fees
Stay at this spa hotel in Panama City. Enjoy free Wi-Fi, a full-service spa and breakfast (surcharge). Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,008 reviews)
Great views and breakfast!

Reviewed on 1 Jan 2026

Las Americas Golden Tower Panama
Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

3.5 out of 5
Italy Avenue, Punta Paitilla Panama City Panama
The price is Rp2.646.804 per night from 19 Jan to 20 Jan
Rp2.646.804
Rp2.911.484 total
19 Jan - 20 Jan
includes taxes & fees
Stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the pool in their ...
9.2/10 Wonderful! (2,165 reviews)
The room was very nice with wrap around windows to see the skyline. Beds comfortable, breakfast was very good.

Reviewed on 6 Jan 2026

Plaza Paitilla Inn Hotel
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
The price is Rp2.290.032 per night from 14 Jan to 15 Jan
Rp2.290.032
Rp2.519.036 total
14 Jan - 15 Jan
includes taxes & fees
Stay at this 4-star spa resort in Panama City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.4/10 Very Good! (1,003 reviews)
Our stay was exceptional overall, and we truly enjoyed our time at the hotel. The room was comfortable, the atmosphere was relaxing, and the service across the property was very good. We stayed in room 1122, and while nothing took away from the quality of our stay, there were a few maintenance items ...

Reviewed on 5 Jan 2026

Sheraton Grand Panama
JW Marriott Panama

JW Marriott Panama

5 out of 5
Calle Punta Colon, Punta Pacifica Panama City Panama
The price is Rp4.335.660 per night from 7 Feb to 8 Feb
Rp4.335.660
Rp4.769.226 total
7 Feb - 8 Feb
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy free Wi-Fi, 4 outdoor pools and 3 restaurants. Our guests praise the helpful staff in their reviews. Popular ...
8.8/10 Excellent! (1,010 reviews)
Nice staff probably one of the best hotel I’ve been to.

Reviewed on 31 Dec 2025

JW Marriott Panama
Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
Avenida Balboa Con Multicentro Panama City Panama
Stay at this spa hotel in Panama City. Enjoy free breakfast, free Wi-Fi and free valet parking. Our guests praise the breakfast and the helpful staff in their ...
8.4/10 Very Good! (1,474 reviews)
Everyone was very friendly and helpful

Reviewed on 1 Jan 2026

Decapolis Hotel Panama City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around San Francisco

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Obarrio

Unique features of Obarrio include the casinos and coffee shops. Make a stop by Calle 50 or Soho City Center while you're exploring the area.

Obarrio
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Punta Pacifica

Notable for its seaside views, restaurants and casinos, Punta Pacifica is a sought-after destination for many travellers visiting Panama City. If you want to see some sights in the area, check out Avenida Balboa or Multiplaza Pacific Mall.

Punta Pacifica
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Punta Paitilla

Punta Paitilla is known for its abundant dining options, and you can plan a trip to Avenida Balboa and Multicentro Panama while you're in town.

Punta Paitilla
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Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Crown Casino.

Bella Vista
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Pueblo Nuevo

While there might not be top attractions in Pueblo Nuevo, you can explore the larger area and discover places like El Dorado Mall and Multiplaza Pacific Mall.

Pueblo Nuevo
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Campo Alegre

3.5/5(5 area reviews)

If you're spending some time in Campo Alegre, Uruguay Street and Calle 50 are top sights worth seeing.

Campo Alegre


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