San Francisco Travel Guide

Panama City

Photo by Hideki Yamagata
Photo by ‎James Barrow
Photo by Adrian Damian
Photo by Nóra Széll
Photo by Panama Roadrunner

Popular places to visit

Things to do


Top hotels in San Francisco

Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa, Panama City
The price is Rp2.151.512 per night from 23 Nov to 24 Nov
Rp2.151.512
Rp2.366.663 total
23 Nov - 24 Nov
includes taxes & fees
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...
8.4/10 Very Good! (1,174 reviews)
Room was excellent

Reviewed on 2 Nov 2025

Megapolis Hotel Panamá
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is Rp2.245.185 per night from 15 Nov to 16 Nov
Rp2.245.185
Rp2.469.704 total
15 Nov - 16 Nov
includes taxes & fees
Stay at this 4-star spa resort in Panama City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.4/10 Very Good! (972 reviews)
Excelente atención y servicio La cuna de bebé era de material como fierro, insegura para bebés que ya se paran un poco El área de juegos de niños siempre mojada y no tenía protección solar podría adecuarse mejor

Reviewed on 1 Nov 2025

Sheraton Grand Panama
Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

3.5 out of 5
Italy Avenue, Punta Paitilla, Winston Churchill Street, Panama City, Panama
The price is Rp2.629.570 per night from 9 Nov to 10 Nov
Rp2.629.570
Rp2.892.527 total
9 Nov - 10 Nov
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in Panama City. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the pool ...
9.2/10 Wonderful! (2,125 reviews)
Clean room, excelent breakfast, good driver for the transportation, excellent staff, very kind

Reviewed on 29 Oct 2025

Plaza Paitilla Inn Hotel
JW Marriott Panama

JW Marriott Panama

5 out of 5
Calle Punta Colon, Punta Pacifica, Panama City, Panama
The price is Rp3.475.879 per night from 23 Nov to 24 Nov
Rp3.475.879
Rp3.823.467 total
23 Nov - 24 Nov
includes taxes & fees
Stay at this 5-star luxury hotel in Panama City. Enjoy free Wi-Fi, 4 outdoor pools and 3 restaurants. Our guests praise the helpful staff and the property condition ...
8.8/10 Excellent! (1,014 reviews)
Yea bar was well stocked

Reviewed on 1 Nov 2025

JW Marriott Panama
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53, Paitilla, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is Rp2.049.438 per night from 15 Nov to 16 Nov
Rp2.049.438
Rp2.254.332 total
15 Nov - 16 Nov
includes taxes & fees
Stay at this 4-star spa hotel in Panama City. Enjoy free Wi-Fi, a full-service spa and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,028 reviews)
Nice clean spacious room

Reviewed on 1 Nov 2025

Las Americas Golden Tower Panama
Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica

4 out of 5
Via Israel y Calle 71, San Francisco, Panama City, Panama
The price is Rp1.696.362 per night from 6 Nov to 7 Nov
Rp1.696.362
Rp1.865.998 total
6 Nov - 7 Nov
includes taxes & fees
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free breakfast, free Wi-Fi and room service. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,091 reviews)
The food was not good on some days

Reviewed on 2 Nov 2025

Ramada Plaza by Wyndham Panama Punta Pacifica
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around San Francisco

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Obarrio

Unique features of Obarrio include the casinos and coffee shops. Make a stop by Calle 50 or Soho City Center while you're exploring the area.

Obarrio
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Punta Pacifica

Notable for its seaside views, restaurants and casinos, Punta Pacifica is a sought-after destination for many travellers visiting Panama City. If you want to see some sights in the area, check out Avenida Balboa or Multiplaza Pacific Mall.

Punta Pacifica
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Punta Paitilla

Punta Paitilla is known for its abundant dining options, and you can plan a trip to Avenida Balboa and Multicentro Panama while you're in town.

Punta Paitilla
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Campo Alegre

3.5/5(5 area reviews)

If you're spending some time in Campo Alegre, Uruguay Street and Calle 50 are top sights worth seeing.

Campo Alegre
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El Cangrejo

4/5(5 area reviews)

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

El Cangrejo
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Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

Bella Vista


San Francisco Travel Guide