A grand church interior with high vaulted ceilings, large columns, and a central altar.

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Our top choices for Santo Spirito hotels

La Torre Del Cestello

La Torre Del Cestello
Santo Spirito
9.0 out of 10, Wonderful, (273 reviews)
"Great location in Oltrarno; clean, comfortable and well-appointed room; helpful and responsive staff. Ask for restaurant recommendations, they won’t disappoint."
United States
Robert
The price is Rp1.950.003
Rp2.432.923 total
includes taxes & fees
4 Jul - 5 Jul
La Torre Del Cestello

Mamo Florence - Bice & Krizia Apartments

Mamo Florence - Bice & Krizia Apartments
Santo Spirito
8.0 out of 10, Very good, (5 reviews)
"Very nice apartment and great location. The included parking and laundry facilities were the reason we selected the property, and were very happy with everything. Overall a lovely stay. "
United States
Michele
The price is Rp1.985.975
Rp4.899.248 total
includes taxes & fees
29 Jul - 30 Jul
Mamo Florence - Bice & Krizia Apartments

Foresteria Valdese di Firenze - Casa per Ferie

Foresteria Valdese di Firenze - Casa per Ferie
Santo Spirito
8.8 out of 10, Excellent, (227 reviews)
"Great stay"
United States
Eric
The price is Rp1.955.503
Rp2.396.188 total
includes taxes & fees
5 Jul - 6 Jul
Foresteria Valdese di Firenze - Casa per Ferie

Hotel Horto Convento

Hotel Horto Convento
4.0 star property
Santo Spirito
9.8 out of 10, Exceptional, (681 reviews)
"Beautiful hotel, comfortable bed and well-appointed room. The friendly staff helped with directions, restaurant recommendations, and reservations. Good breakfast, great bartender at the bar in the lobby. Would stay again and highly recommend."
United States
Mari
The price is Rp3.440.981
Rp4.072.999 total
includes taxes & fees
19 Jul - 20 Jul
Hotel Horto Convento

Oltrarno Splendid

Oltrarno Splendid
Santo Spirito
10.0 out of 10, Exceptional, (128 reviews)
"We absolutely loved our 3-night stay at Oltrarno Splendid - a true hidden Gem in the best location - with cool shopping vibes and on the quieter side of the river! We loved the neighborhood feel and soaring ceilings for an authentice Florence stay with all the modern ammenities. Beautiful breakfast included and exceptionally friendly, helpful staff - shout-outs to Davide & Barbara!"
Canada
Leanne
The price is Rp4.830.259
Rp5.599.275 total
includes taxes & fees
29 Jul - 30 Jul
Oltrarno Splendid

AdAstra Suites

AdAstra Suites
Santo Spirito
9.8 out of 10, Exceptional, (231 reviews)
"What a special place! Beautiful place, large room and beautifully garden and comfortable and welcoming gathering/common area space where we were treated like old friends. Cannot wait to return."
United States
Mary Clare
The price is Rp4.475.094
Rp5.208.593 total
includes taxes & fees
27 Jul - 28 Jul
AdAstra Suites

Ottantotto Firenze

Ottantotto Firenze
Santo Spirito
9.6 out of 10, Exceptional, (174 reviews)
"Really beautiful property and wonderful room. Hotel is immaculately clean and we thought the hotel had been renovated to a beautiful finish. We let the hotel know we were staying for our 10 year anniversary, and a bottle of Prosecco was left in our room with a note, which was extremely kind. A great location to stay in, just across the river. Passcode is provided for front door so can come and go as please. Have booked to stay in again in October!"
United Kingdom
Samantha
The price is Rp3.683.060
Rp4.337.356 total
includes taxes & fees
14 Jul - 15 Jul
Ottantotto Firenze

L'Antica Porta Boutique B&B

L'Antica Porta Boutique B&B
Santo Spirito
8.6 out of 10, Excellent, (26 reviews)
"Very goord place to stay"
United States
Victor
The price is Rp1.968.700
Rp2.412.359 total
includes taxes & fees
2 Aug - 3 Aug
L'Antica Porta Boutique B&B

Fiammetta by MMega

Fiammetta by MMega
Santo Spirito
The price is Rp2.141.861
Rp4.439.688 total
includes taxes & fees
26 Jul - 27 Jul
Fiammetta by MMega

La Fonderia Firenze

La Fonderia Firenze
Santo Spirito
9.6 out of 10, Exceptional, (183 reviews)
"Really nice, handy location"
United Kingdom
Kate
The price is Rp2.170.137
Rp2.632.285 total
includes taxes & fees
19 Jul - 20 Jul
La Fonderia Firenze

Casa Vittoria by Mmega

Casa Vittoria by Mmega
Santo Spirito
2.0 out of 10, (1 review)
"El trato de la persona a cargo fue terrible nos cobró extra del precio de la renta 90 euros de limpieza solo en efectivo con una actitud muy arrogante más $35 por llegar una hora tarde después de su checkin, nunca tuvimos internet lo cual le avisamos a la brevedad y su respuesta fue que el no tenía el internet en su cartera! Terrible el trato! Nunca regresó a arreglar el internet! En la casa no hay señal y tampoco internet! "
Mexico
Estefania
The price is Rp1.622.715
Rp3.868.627 total
includes taxes & fees
13 Jul - 14 Jul
Casa Vittoria by Mmega

Mamo Florence - Aleardi Roof Apartment

Mamo Florence - Aleardi Roof Apartment
Santo Spirito
10.0 out of 10, Exceptional, (1 review)
"Excelente lugar y relacion precio - estancia"
Mexico
Roberto Carlos
The price is Rp1.649.531
Rp4.408.821 total
includes taxes & fees
5 Jul - 6 Jul
Mamo Florence - Aleardi Roof Apartment

Vettori Hideaway by MMega

Vettori Hideaway by MMega
Santo Spirito
The price is Rp1.644.238
Rp3.892.302 total
includes taxes & fees
1 Aug - 2 Aug
Vettori Hideaway by MMega

Palazzo Mannaioni Suites

Palazzo Mannaioni Suites
4.0 star property
Santo Spirito
9.2 out of 10, Wonderful, (1,134 reviews)
"The management waswarm and welcoming and helped assist us with restaurants, travel and sightseeing."
United States
Janet
The price is Rp2.941.611
Rp3.521.762 total
includes taxes & fees
5 Jul - 6 Jul
Palazzo Mannaioni Suites

1900 Artevita

1900 Artevita
Santo Spirito
8.8 out of 10, Excellent, (195 reviews)
"Pros: - great location. In quiet neighbourhood yet walkable to everywhere. Close to lovely restaurants and bakery. - "
United Kingdom
Jennifer
The price is Rp1.722.191
Rp2.141.199 total
includes taxes & fees
2 Aug - 3 Aug
1900 Artevita

Cosimo by MMega

Cosimo by MMega
Santo Spirito
9.2 out of 10, Wonderful, (18 reviews)
"Beautiful place, clean specious rooms, great location. There were all needed amenities: laundry, dishwasher, hairdryer and etc. Highly recommend!"
United States
Oxana
The price is Rp1.947.146
Rp4.429.780 total
includes taxes & fees
21 Jul - 22 Jul
Cosimo by MMega

Drom Florence Rooms & Apartments

Drom Florence Rooms & Apartments
Santo Spirito
9.8 out of 10, Exceptional, (151 reviews)
"We had a very nice stay. Claudia was very friendly and service minded The place serves continental breakfast - and is a good idea to supplement it a little bit! Nice and quiet area, where you can walk to most things We can only recommend it Else Marie Hansen May 2026"
Denmark
Else Marie
The price is Rp1.580.755
Rp1.985.620 total
includes taxes & fees
5 Jul - 6 Jul
Drom Florence Rooms & Apartments

Appartamenti degli Artisti by Mmega

Appartamenti degli Artisti by Mmega
Santo Spirito
8.4 out of 10, Very good, (40 reviews)
"Great stay! The place was clean, comfortable, and exactly as described. Would definitely stay again"
United States
Diana
The price is Rp1.448.387
Rp3.485.272 total
includes taxes & fees
2 Aug - 3 Aug
Appartamenti degli Artisti by Mmega

Residenza D'Epoca Al Numero 8

Residenza D'Epoca Al Numero 8
Santo Spirito
9.0 out of 10, Wonderful, (158 reviews)
"Excellent place"
United States
Laura Patricia
The price is Rp1.950.003
Rp2.432.923 total
includes taxes & fees
4 Jul - 5 Jul
Residenza D'Epoca Al Numero 8

Palazzo Oliveto

Palazzo Oliveto
Santo Spirito
7.6 out of 10, Good, (102 reviews)
"Good location"
France
Leana
The price is Rp1.145.390
Rp1.505.063 total
includes taxes & fees
17 Jul - 18 Jul
Palazzo Oliveto
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santo Spirito

Find the best Santo Spirito areas for the activities you enjoy most.

Historic Centre of Florence

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Duomo

Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Cathedral of Santa Maria del Fiore or Uffizi Gallery while you're exploring the neighbourhood.

San Giovanni

If you're spending some time in San Giovanni, Piazza della Signoria and Uffizi Gallery are top sights worth seeing.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

Santa Croce

Santa Croce is known for its interesting museums, and you can plan a trip to Basilica of Santa Croce and Piazza Santa Croce while you're in town.

Top Santo Spirito Hotel Reviews

Find out more about Santo Spirito

Top reasons to visit Santo Spirito

  • Charming Piazza Santo Spirito: Experience the vibrant atmosphere and friendly locals in this picturesque square.
  • Historic San Spirito Church: Visit this remarkable church to appreciate its stunning architecture and rich history.
  • Bustling Public Market: Explore local treasures and savour the flavours of Tuscany at the lively market.
  • Delightful Wine Tours: Indulge in exquisite wine tastings that showcase the best of Tuscan vineyards.
  • Diverse Accommodation Options: Choose from stylish hotels and cosy bed & breakfasts for a personalised stay.

Find great hotels near Santo Spirito

Discover the charm of Santo Spirito with a range of delightful accommodation options, including stylish hotels and cosy bed & breakfasts. Whether you're seeking a city-themed experience or a pet-friendly retreat, you'll find personalised services and unique touches, such as antique furniture and the inviting atmosphere of Palazzo Ridolfi. Enjoy your stay in Florence, where every corner offers a glimpse of history and artistry.

  • The Social Hub Florence Lavagnini: A vibrant 4-star hotel that caters to adventurous spirits and business travellers alike. With a commendable guest rating of 9.0 out of 10, this accommodation is located 2km from Santo Spirito. The Social Hub Florence Lavagnini offers a unique blend of contemporary design and engaging social spaces, making it an ideal choice for those seeking a lively atmosphere. Guests can indulge in various adventure sports and recreational activities either onsite or nearby, ensuring an exciting stay in Florence.
  • B&B Hotel Firenze Pitti Palace al Ponte Vecchio: This charming 4-star property, with a guest rating of 9.0 out of 10, is situated 1km from Santo Spirito. The B&B Hotel Firenze Pitti Palace al Ponte Vecchio is well-suited for families looking for adventure and memorable experiences. With amenities like bicycle rentals available in the vicinity, guests can easily explore the stunning surroundings. The hotel also provides thoughtful services for children, including babysitting and childcare options, making it a family-friendly choice for your stay in Florence.
  • Grand Hotel Cavour: Rated at an impressive 9.2 out of 10, this 4-star hotel is located 2km from Santo Spirito, nestled in a bustling shopping district. The Grand Hotel Cavour is perfect for families and shopping enthusiasts, with a range of amenities tailored for children, including in-room and onsite babysitting services. The hotel’s elegant design and proximity to shopping make it a desirable base for those looking to enjoy both cultural attractions and retail therapy while in Florence.

Where to stay near Santo Spirito

Santo Spirito, nestled in the heart of Florence, offers a vibrant blend of culture and history. Wander through the charming Piazza Santo Spirito, where friendly locals and a romantic atmosphere await. Explore the rich Florentine Renaissance heritage while enjoying trendy cafes and secluded spots. This neighbourhood is perfect for those seeking a luxury experience or a relaxing getaway, making it an ideal base to discover the enchanting essence of Florence and its surroundings.

  • Florence: As the cradle of the Renaissance, Florence boasts an extraordinary blend of art, culture, and history. Located in the heart of Tuscany, this vibrant city attracts visitors year-round, with peak seasons in March to April and September. Here, you can immerse yourself in world-renowned museums, stunning architecture, and charming piazzas. Explore the Uffizi Gallery, marvel at the Florence Cathedral, and stroll across the iconic Ponte Vecchio. The lively atmosphere is complemented by a variety of shopping areas, spas, and theatres, making it an ideal destination for families and culture enthusiasts alike.
  • Duomo: Just 1km from Santo Spirito, the Duomo neighbourhood is famous for its magnificent cathedral, Santa Maria del Fiore, with its striking dome designed by Brunelleschi. This area experiences moderate seasonal fluctuations in visitor numbers, peaking during the summer months. Duomo offers a delightful mix of bustling markets, public squares, and shopping areas, perfect for those looking to immerse themselves in local life. Be sure to wander through the nearby historic sites and enjoy the vibrant street performances that often take place in the piazzas.
  • San Giovanni: Also located 1km from Santo Spirito, San Giovanni is a charming neighbourhood known for its rich history and cultural offerings. Visitors flock here during the summer, making it a lively spot for family-friendly activities and cultural experiences. The area features a blend of shopping areas and public markets, where you can find local delicacies and artisan products. Don’t miss the chance to visit the historic landmarks and picturesque squares that define this enchanting part of Florence.

Things to do near Santo Spirito

Shopping

Santo Spirito offers a charming shopping experience with local boutiques and artisan shops. Explore the vibrant Mercato di Santo Spirito for unique souvenirs, or visit nearby artisan workshops for handmade crafts. Enjoy a leisurely stroll through the area to discover hidden gems and delightful gifts.

Recreation

In Santo Spirito, unwind at the luxurious Villa Cora, where rejuvenating spa treatments and serene gardens create a tranquil escape. Explore the nearby Giardino di Boboli, offering peaceful walks and stunning views, perfect for relaxation amidst nature's beauty.

Adventure

Experience the thrill of motor racing at Mugello Circuit, located 27km from Santo Spirito. Feel the adrenaline rush as you witness high-speed races and enjoy the vibrant atmosphere, perfect for motorsport enthusiasts and adventure seekers alike.

Nightlife

Santo Spirito buzzes with life after dark. Enjoy a glass of wine at Le Volpi e L’Uva, or dive into the vibrant atmosphere at the lively Caffè degli Artigiani. For a laid-back vibe, try the rustic charm of Il Santo Bevitore, where you can unwind with friends.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Santo Spirito

Santo Spirito offers budget-friendly travel options for visitors. The best months to save on accommodation are January, February, and November, while Mondays typically offer the lowest rates. For optimal deals, book your hotel at least a month in advance or explore last-minute offers on Expedia. Consider using public transport, which is economical and convenient. Additionally, many attractions in the area can be enjoyed for free, such as exploring the charming streets and local markets. Combining your hotel, flights, and activities into a package can yield significant savings.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Santo Spirito are January to February and November, where the prices are slightly lower. This is in comparison to May to June and September, where prices are slightly higher.
  • The best time to book a hotel: The cheapest time to book a hotel around Santo Spirito is usually 1 month out from when you are planning to stay. If you're a little more spontaneous, you could also peruse Expedia's last minute deals which could secure you a cheaper stay. Look out for the green banner below the price to spot the deals.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Santo Spirito is Monday. The most expensive day to stay around Santo Spirito is Friday.
  • Find cheap hotels on Expedia: Utilise Expedia's search tool to refine your preferences, including your budget, preferred location, and desired type of accommodation. For instance, selecting the Eco-certified option will reveal sustainable and environmentally-friendly hotels currently available. To find the most affordable prices and offers, arrange the price filter from low to high.
  • Consider bundling your trip: You can make significant savings by combining your hotel reservation in Santo Spirito with your flights and activities through an Expedia package.

Find the best attractions near Santo Spirito

Santo Spirito offers a delightful blend of culture, city exploration, and outdoor activities. Visitors can enjoy the charming Santo Spirito Square, visit the historic San Spirito church, and wander through nearby piazzas and palaces, making it ideal for families and culture enthusiasts alike. Whether you're keen on immersing yourself in local history or simply enjoying the vibrant atmosphere, Santo Spirito is a wonderful destination for a memorable vacation.

  • San Lorenzo Church: Located a mile from Santo Spirito, this church offers a rich cultural atmosphere with its stunning Renaissance architecture and historical significance. Visitors can admire the intricate artworks and the unique layout of the church, which reflects the artistic heritage of Florence.
  • Marsilis Tower: Just 1km away, this historic tower stands as a testament to Florence's medieval past. Its impressive structure and surrounding views provide a glimpse into the city's rich history, making it an intriguing spot for history enthusiasts.
  • Piazza di Santa Maria Novella: Situated 1km from Santo Spirito, this vibrant square is a hub of urban life and culture. Surrounded by beautiful architecture and lively cafés, it's an ideal place to soak in the Florentine atmosphere while enjoying the local scene.

Best time to go to Santo Spirito

The best time to visit Santo Spirito can depend on the weather and when visitor numbers rise and fall. The hottest average temperature around Santo Spirito falls in July and August. August has moderately high visitor numbers and sunny weather. The coolest average temperature around Santo Spirito falls in January, visitor numbers are moderately low and weather is mostly sunny with light rain.

calendar iconCalendar Monthtemperature iconTemperaturerain iconPrecipitationmostly cloudy iconCloudinessoccupation rate iconOccupancyprice iconPricing
January41.4°F (5.2°C)Light RainMostly SunnyModerately LowSlightly Low
February43.0°F (6.1°C)Light RainMostly SunnyModerately LowSlightly Low
March47.8°F (8.8°C)Light RainMostly SunnyAverageAverage
April54.3°F (12.4°C)Light RainMostly SunnyAverageAverage
May60.4°F (15.8°C)Light RainMostly SunnyAverageSlightly High
June69.6°F (20.9°C)Light RainSunnyAverageSlightly High
July75.2°F (24.0°C)No RainSunnyModerately HighAverage
August75.2°F (24.0°C)No RainSunnyModerately HighAverage
September67.3°F (19.6°C)Light RainMostly SunnyModerately HighSlightly High
October58.8°F (14.9°C)Light RainMostly SunnyAverageAverage
November50.2°F (10.1°C)Light RainMostly SunnyAverageSlightly Low
December43.5°F (6.4°C)Light RainMostly SunnyModerately LowAverage

The nearest major airports for your trip to Santo Spirito

Reaching Santo Spirito in Florence, Tuscany, is convenient via Florence Airport (FLR-Peretola), located 5km away. Notable hotels nearby include the 5-star Hotel Lungarno, just 5km from the airport, offering transfers and shuttles. The Bernini Palace, situated 6km away, also provides various transportation services, including an airport shuttle. For those considering Bologna Airport (BLQ-Guglielmo Marconi), located 85km away, the Grand Hotel Majestic and Starhotels Excelsior are excellent 5-star options, both 5km from the airport and offering shuttle services. Pisa Airport (PSA-Galileo Galilei) is 68km from Santo Spirito, with the 5-star Hotel Pisa Tower Plaza just 3km from the airport.

Frequently asked questions

What is Santo Spirito like?
Santo Spirito is a trendy neighbourhood known for its stunning river views. Make sure that you visit Piazza Santo Spirito and Santo Spirito Basilica as part of your Santo Spirito travel plans.
What's a favourite place to stay in Santo Spirito?
Based on our traveller data, Hotel Horto Convento is one of the top choices for your stay in Santo Spirito. This hotel is a short 14-minute walk from Piazza di Santa Maria Novella, and it offers free breakfast and a bar. Other good options for your stay in the neighbourhood include La Torre Del Cestello and UNA Hotels Vittoria Firenze.
How many hotels can I expect to find in the Santo Spirito area?
Expedia has 512 hotels and other accommodation options in Santo Spirito to choose from, making this an ideal home base for exploring the greater Florence area.
If I need to cancel my hotel reservation in Santo Spirito, will I receive a refund?
Yes, the majority of hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within 24 hours of booking. Enter dates in and click on "Search", then filter by "fully refundable" to get top deals in Santo Spirito.
What can I see and do in this Florence neighbourhood?
Spend some time exploring the natural setting of Santo Spirito with a visit to Arno River and Torrigiani Garden. As you're discovering the neighbourhood, Piazza Santo Spirito and Santo Spirito Basilica are some other places worth a visit. Favourite places to visit in the surrounding area include Piazza di Santa Maria Novella, Uffizi Gallery and Piazza della Signoria. When you're sightseeing in Florence, Cathedral of Santa Maria del Fiore and Piazza del Duomo are also worth a stop.