Santo Spirito Travel Guide
Florence





Visit Santo Spirito
Top hotels in Santo Spirito

Hotel Horto Convento
Excellent staff, so friendly and helpful. Lovely hotel in a great location.
Reviewed on 7 Nov 2025

Palazzo Mannaioni Suites
Clean and great staff
Reviewed on 8 Nov 2025

UNA Hotels Vittoria Firenze
Super nice reception staffs, everyone is so friendly and welcoming. But don’t like the red room decoration.
Reviewed on 5 Nov 2025

La Torre Del Cestello
Staff were super friendly, the room and the view from the room were gorgeous, location was perfect. I would happily stay again and recommend to anyone heading to Florence for holiday.
Reviewed on 6 Nov 2025

Hostel Santa Monaca
Clean room , friendly staffs & very accessible to any amenities . Separate toilet , shower & lavatory specific for women only , away from male rooms & toilets . Have ample space for kitchen with utensils, tables & chairs . Highly recommended ! Love it
Reviewed on 18 Sept 2025

Oltrarno Splendid
Amazing and kind staff. Delicious breakfast.
Reviewed on 18 Oct 2025
Other neighbourhoods around Santo Spirito

San Frediano
San Frediano is known for its stunning river views, and you can plan a trip to Piazza Santo Spirito and Santo Spirito Basilica while you're in town.

Oltrarno
Oltrarno is a destination visitors seek out for its fascinating museums, picturesque gardens and beautiful river views. You might also want to check out attractions like Pitti Palace or Pitti Vintage while you're exploring the neighbourhood.

Santa Maria Novella
Enjoy the popular shops in Santa Maria Novella. The New Florence Opera House is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

San Giovanni
If you're spending some time in San Giovanni, Uffizi Gallery and Cathedral of Santa Maria del Fiore are top sights worth seeing.

Duomo
Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Cathedral of Santa Maria del Fiore or Uffizi Gallery while you're exploring the neighbourhood.

Historic Centre of Florence
Known for its fascinating museums, stunning cathedral and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Cathedral of Santa Maria del Fiore and Uffizi Gallery are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.
