Santo Spirito Travel Guide

Florence

A grand church interior with high vaulted ceilings, large columns, and a central altar.
A stone bridge over a calm river, with historic buildings on either side.
A bustling outdoor market with white tents and various stalls.
A church with a bell tower, a circular window, and a weather vane.
A cityscape with a river, a bridge, and mountains in the background.

Stay near popular Santo Spirito attractions

A town square with historic buildings, a church, and a bell tower.

Piazza Santo Spirito

9.6/10 (8 reviews)
Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the fascinating museums and notable monuments in this vibrant area.
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Things to do

Tuscany Experience In Pisa, Siena, San Gimignano & Chianti

Tuscany Experience In Pisa, Siena, San Gimignano & Chianti

Rp1.340.440
per adult
92% of travellers recommend
Tuscany Experience In Pisa, Siena, San Gimignano & Chianti
The Best of Tuscany in One Day Sightseeing Tour

The Best of Tuscany Tour: Siena, San Gimignano, Pisa and Lunch at a Winery

Rp1.402.306
per adult
98% of travellers recommend
The Best of Tuscany Tour: Siena, San Gimignano, Pisa and Lunch at a Winery
People riding scooters in Tuscany

Florence Vespa Tour: Tuscan Hills, Food and Chianti Wine

Rp2.278.747
per adult
100% of travellers recommend
Florence Vespa Tour: Tuscan Hills, Food and Chianti Wine
Ticket to Brunelleschi's Dome

Skip the line ticket & Audio guide to Brunelleschi's Dome

Rp1.216.707
per adult
Skip the line ticket & Audio guide to Brunelleschi's Dome
Michaelangelo's David

Accademia timed-entry Ticket with Instant Delivery & Priority Access

Rp845.508
per adult
94% of travellers recommend
Accademia timed-entry Ticket with Instant Delivery & Priority Access
Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour

Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour

Rp489.776
per adult
80% of travellers recommend
Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour
See all activities in Florence

Top hotels in Santo Spirito

Hotel Horto Convento

Hotel Horto Convento

4 out of 5
Viale Ariosto, 13 Florence FI
Fully refundableReserve now, pay when you stay
The price is Rp3.257.088 per night from 13 Aug to 14 Aug
Rp3.257.088
Rp3.868.734 total
13 Aug - 14 Aug
includes taxes & fees
Stay at this hotel in Florence. Enjoy free breakfast, free Wi-Fi and room service. Our guests praise the breakfast and the helpful staff in their reviews. Popular ...
9.8/10 Exceptional! (696 reviews)
"The staff friendly, welcoming, and very helpful. Centrally located and the perfect spot to explore the city on foot. I will definitely return."

Reviewed on 22 Jul 2026

Hotel Horto Convento
La Torre Del Cestello

La Torre Del Cestello

Via Borgo San Frediano, 8 Florence FI
The price is Rp1.850.151 per night from 31 Jul to 1 Aug
Rp1.850.151
Rp2.321.103 total
31 Jul - 1 Aug
includes taxes & fees
Stay at this residence in Florence. Enjoy free Wi-Fi, valet parking (surcharge) and daily housekeeping. Popular attractions Ponte Vecchio and Piazza della Signoria ...
9/10 Wonderful! (282 reviews)
"Everything was great!"

Reviewed on 25 Jul 2026

La Torre Del Cestello
UNA Hotels Vittoria Firenze

UNA Hotels Vittoria Firenze

4 out of 5
Via Pisana 59 Florence FI
The price is Rp1.654.352 per night from 2 Aug to 3 Aug
Rp1.654.352
Rp2.105.724 total
2 Aug - 3 Aug
includes taxes & fees
Stay at this boutique hotel in Florence. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff in their reviews. Popular ...
8.4/10 Very good! (1,000 reviews)
"Great staff and well located especially for the West Bank of the city. Slightly too far out for the city etc"

Reviewed on 12 May 2026

UNA Hotels Vittoria Firenze
Foresteria Valdese di Firenze - Casa per Ferie

Foresteria Valdese di Firenze - Casa per Ferie

Via dei Serragli 49 Florence FI
The price is Rp1.337.037 per night from 4 Aug to 5 Aug
Rp1.337.037
Rp1.715.830 total
4 Aug - 5 Aug
includes taxes & fees
Stay at this guesthouse in Florence. Enjoy free Wi-Fi, 2 meeting rooms and satellite TV channels. Our guests praise the helpful staff and the clean rooms in ...
8.8/10 Excellent! (231 reviews)
"Conveniently located. Monica was super helpful. I would definitely stay there again."

Reviewed on 20 Jul 2026

Foresteria Valdese di Firenze - Casa per Ferie
Palazzo Mannaioni Suites

Palazzo Mannaioni Suites

4 out of 5
Via Maffia 9 - 17r Florence FI
The price is Rp3.826.660 per night from 5 Aug to 6 Aug
Rp3.826.660
Rp4.495.345 total
5 Aug - 6 Aug
includes taxes & fees
Stay at this residence in Florence. Enjoy free Wi-Fi, concierge services and premium bedding. Our guests praise the helpful staff in their reviews. Popular attractions ...
9.2/10 Wonderful! (1,147 reviews)
"Lovely place, perfect location. Easy to access!"

Reviewed on 25 Jul 2026

Palazzo Mannaioni Suites
Torre di Bellosguardo

Torre di Bellosguardo

4 out of 5
Via Roti Michelozzi 2 Florence FI
The price is Rp9.966.963 per night from 31 Jul to 1 Aug
Rp9.966.963
Rp11.249.597 total
31 Jul - 1 Aug
includes taxes & fees
Stay at this business-friendly hotel in Florence. Enjoy free Wi-Fi, free parking and an outdoor pool. Popular attractions Ponte Vecchio and Piazza della Signoria ...
9/10 Wonderful! (103 reviews)
"This was by far the best hotel I have ever stayed at, as someone who travels solo often sometimes you are just looking for some peace and not having to do everything on your own. I am in awe of the property. If you are looking for privacy, story book views, and gardens this is the place to be. The ..."

Reviewed on 29 Oct 2025

Torre di Bellosguardo
See all 523 properties in Santo Spirito
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santo Spirito

Find the best Santo Spirito areas for the activities you enjoy most.
A river with buildings on the right bank.

Historic Centre of Florence

Known for its fascinating museums, stunning cathedral and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Cathedral of Santa Maria del Fiore and Piazza della Signoria are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.

A historic building with intricate architectural details, including a dome and ornate facades.

Duomo

Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Cathedral of Santa Maria del Fiore or Piazza del Duomo while you're exploring the neighbourhood.

A historic bridge with arches over a river, surrounded by yellow buildings and a crowd of people.

San Giovanni

If you're spending some time in San Giovanni, Piazza della Signoria and Cathedral of Santa Maria del Fiore are top sights worth seeing.

A historic church with intricate architecture and a large open plaza with people.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

An ornate building with intricate architectural details and a clear blue sky in the background.

Santa Croce

Santa Croce is known for its interesting museums, and you can plan a trip to Basilica of Santa Croce and Piazza Santa Croce while you're in town.

Santo Spirito Travel Guide