Santo Spirito Holidays

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    Save up to Rp16.000.000 when you book a flight and hotel together*

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Where to stay in Santo Spirito

Find the best Santo Spirito areas and neighborhoods for the activities you enjoy most. Learn more about Santo Spirito
Historic Centre of Florence

Historic Centre of Florence

10 out of top 10 points of interest in this area

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Find hotels in Historic Centre of Florence

Top hotels in Santo Spirito

Hotel Horto Convento

Hotel Horto Convento

4 out of 5
Viale Ariosto, 13 Florence FI
Fully refundableReserve now, pay when you stay
The price is Rp5.833.353 per night from 7 Jun to 8 Jun
Rp5.833.353
Rp6.704.045 total
7 Jun - 8 Jun
includes taxes & fees
9.8/10 Exceptional! (660 reviews)
"Amazing stay! Beautiful property! The spa is a wonderful amenity."

Reviewed on 18 May 2026

Hotel Horto Convento
Palazzo Mannaioni Suites

Palazzo Mannaioni Suites

4 out of 5
Via Maffia 9 - 17r Florence FI
Fully refundableReserve now, pay when you stay
The price is Rp5.306.668 per night from 1 Jun to 2 Jun
Rp5.306.668
Rp6.124.610 total
1 Jun - 2 Jun
includes taxes & fees
9.2/10 Wonderful! (1,115 reviews)
"They staff were incredibly helpful and welcoming. They gave good recommendations. The location was impeccable with a wine window less than a block away. Good gelato not far away and a fun bar around the corner Spirituum Spirits Bar had excellent espresso martinis. I would skip Braceria as the other ..."

Reviewed on 21 May 2026

Palazzo Mannaioni Suites
La Torre Del Cestello

La Torre Del Cestello

Via Borgo San Frediano, 8 Florence FI
Fully refundableReserve now, pay when you stay
The price is Rp4.164.814 per night from 7 Jun to 8 Jun
Rp4.164.814
Rp4.868.652 total
7 Jun - 8 Jun
includes taxes & fees
La Torre Del Cestello
See all 498 properties in Santo Spirito
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santo Spirito holiday package cost?
From just . Yes, you read that right. Our Santo Spirito packages are the best way to make your dollar go further. Bundle your favourite hotels, flights and rental car and explore this wonderful destination.
How do I get a cheap travel package to Santo Spirito?
If you love scoring a bargain, bundle your bookings into a Santo Spirito holiday package. Whether you need hotels, flights, activities or rental cars, you can book everything in one place. You'll have endless choice at your fingertips as well. Expedia has more than 550 partner airlines and 1,000,000 hotels across the globe to choose from. Fly with who you want, stay in a place you like and save precious dollars — now that's the ideal getaway!
What are the top hotels in Santo Spirito?
Reserve a room at Sweet Home Campuccio, 2 Double Bedrooms In San Frediano. It's one of this area's most sought-after hotels. Another well-known option in Santo Spirito is Residenza Oltrarno, An Elegant Apartment In The Historic Centre Of Florence.
How far in advance should I book my Santo Spirito holiday?
To score cheap prices, book as soon as you can. Airlines typically release tickets, along with some of the lowest fares, up to a year in advance. Hotels, activities and car rental should also be booked early to avoid disappointment. If you were hoping for a last-minute getaway in Santo Spirito, there are always lots of great deals on Expedia. Check them out now!
What does an Expedia Santo Spirito travel package include?
Rental cars, flights and hotels, or any combination of the three — it's totally up to you. Whether you're headed to Santo Spirito with the entire family or enjoying a solo break, there's a bundle to match every budget and style. Once you've made your booking, why not add on a couple of tours as well?
What should I know before booking a Santo Spirito travel package?
Locking in all the parts of your trip together is one of the best ways to save. Combine car rentals, airfares and hotels into a neat little package. But you're not restricted to hotels. Expedia features all sorts of properties, including holiday rentals like oceanfront condos and city residences. The list goes on!
Can I choose my airline with a Santo Spirito Expedia holiday package?
Yes — and it's simple too. Expedia has access to more than 550 partner airlines all over the world. Our holiday packages give you the freedom to pick from available flights, hotels and activities that suit you.
If I'm not able to travel, can I cancel my Santo Spirito holiday package?
If your holiday plans in Santo Spirito have been upended, it's a relief to know that it is possible to cancel your booking. If you made your booking within the last 24 hours, you may be eligible for a refund. If your booking is older than that, your airline, hotel or car rental company may charge a fee. For more details, check our Customer Service Portal.

Popular places to visit

Il Nabucco di Matteo Gabellini

You can study the exhibits at Il Nabucco di Matteo Gabellini, a museum with a story of its own, during your travels to Florence. Discover the fascinating museums and churches in this vibrant area.

Il Nabucco di Matteo Gabellini

Things to do

Small-Group Wine Tasting Experience in the Tuscan Countryside

Small-Group Wine Tasting Experience in the Tuscan Countryside

Rp1.811.115
per adult
98% of travellers recommend
Small-Group Wine Tasting Experience in the Tuscan Countryside
Florence Accademia Gallery Tour with Entrance Ticket Included

Florence Accademia Gallery Tour with Entrance Ticket Included

Rp976.781
per adult
92% of travellers recommend
Florence Accademia Gallery Tour with Entrance Ticket Included
The Best of Tuscany in One Day Sightseeing Tour

The Best of Tuscany in One Day Sightseeing Tour

Rp2.136.708
per adult
98% of travellers recommend
The Best of Tuscany in One Day Sightseeing Tour
See all activities in Florence
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.