Santo Spirito Travel Guide
Florence
Visit Santo Spirito
Popular places to visit
Piazza Santo Spirito
Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the fascinating museums and stunning cathedral in this vibrant area.
Porta Romana
Find out about the history of Arcetri when you spend time at Porta Romana. Amble around this vibrant area's riverfront or experience its fascinating museums.
Brancacci Chapel
A dazzling array of Renaissance frescoes adorn the walls of the most famous chapel of Florence’s 750-year-old Church of Santa Maria del Carmine.
Santo Spirito Basilica
Learn about the local history of Florence when you take a trip to Santo Spirito Basilica. Stroll along the riverfront or visit the churches in this vibrant area.
Torrigiani Garden
Explore the great outdoors at Torrigiani Garden, a lovely green space in Florence. Stroll along the riverfront or visit the stunning cathedral in this vibrant area.
Santa Maria della Carmine
You can learn about the history of Florence with a visit to Santa Maria della Carmine. Visit the notable monuments and stunning cathedral in this vibrant area.
Things to do
Florence Accademia Gallery Tour with Entrance Ticket Included
Tuscany Experience In Pisa, Siena, San Gimignano & Chianti
Skip the Line: Florence's Accademia Gallery Priority Entrance Ticket
Siena, San Gimignano, Monteriggioni & Chianti from Florence
Pisa, Siena and San Gimignano day trip from Florence
Florence All inclusive City Pass with Uffizi and Accademia entry
Top hotels in Santo Spirito
Palazzo Mannaioni Suites
Loved my stay. Everyone was super friendly, Novellas food recommendations were amazing!! My room was spotless and very quiet at night
Reviewed on 18 Jan 2026
Hotel Horto Convento
Lovely clean, quiet and safe hotel. really good breakfast and staff. Good location within walking distance to everything.
Reviewed on 13 Jan 2026
UNA Hotels Vittoria Firenze
Perfect stay! Not only was the check-in smooth, but everything else was also satisfying. The breakfast was delicious, the staff were friendly, and the location was ideal. There wasn't a single thing I didn't like. I’ll definitely be back!
Reviewed on 1 Jan 2026
Santo Spirito Venti
The Santo Spirito Venti is in a great location if you want to be close to the Piazza Santa Maria Novella area but want to avoid the noise and crowdedness. It is near a lot of good restaurants. The room was clean and there were enough room for my three kids and me. No complaints but some things of ...
Reviewed on 30 Nov 2025
La Torre Del Cestello
The Torre del Cestello had the "Room with a View" (complete with garden below) that I had been dreaming of for my first visit to Florence. The desk staff were all pleasant, helpful, and set me up with a map and suggestions when I checked in. There was easy access in and out of the room. Quiet but ...
Reviewed on 18 Jan 2026
Casa Santo Nome di Gesù
Really a nice place, like the room style and good for family stay!
Reviewed on 1 Jan 2026
Other neighbourhoods around Santo Spirito
San Frediano
San Frediano is known for its stunning river views, and you can plan a trip to Piazza Santo Spirito and Boboli Gardens while you're in town.
Oltrarno
Oltrarno is a destination visitors seek out for its fascinating museums, picturesque gardens and beautiful river views. You might also want to check out attractions like Pitti Palace or Via Maggio while you're exploring the neighbourhood.
Santa Maria Novella
Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.
San Giovanni
If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.
Historic Centre of Florence
Known for its fascinating museums, stunning cathedral and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Piazza di Santa Maria Novella and Via de' Calzaiuoli are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.
Duomo
Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Piazza di Santa Maria Novella or Via de' Calzaiuoli while you're exploring the neighbourhood.
