Santo Spirito Travel Guide
Florence
Visit Santo Spirito
Popular places to visit
Piazza Santo Spirito
Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the fascinating museums and churches in this vibrant area.
Porta Romana
Porta Romana is just one of the places to see in Arcetri, so why not enjoy the other things to explore during your travels? Discover the acclaimed art galleries and churches in this vibrant area.
Brancacci Chapel
A dazzling array of Renaissance frescoes adorn the walls of the most famous chapel of Florence’s 750-year-old Church of Santa Maria del Carmine.
Torrigiani Garden
Explore the great outdoors at Torrigiani Garden, a lovely green space in Florence. Stroll along the riverfront or visit the churches in this vibrant area.
Santo Spirito Basilica
Learn about the local history of Florence when you take a trip to Santo Spirito Basilica. Stroll along the riverfront or visit the churches in this vibrant area.
Santa Maria della Carmine
You can learn about the history of Florence with a visit to Santa Maria della Carmine. Visit the churches and notable monuments in this vibrant area.
Things to do
Small-Group Wine Tasting Experience in the Tuscan Countryside
Florence Accademia Gallery Tour with Entrance Ticket Included
Cinque Terre Experience from Florence
The Best of Tuscany in One Day Sightseeing Tour
Uffizi & Accademia Timed Entry: Small Group Duomo Walking Tour
Florence: San Gimignano, Siena, Monteriggioni, Chianti & Lunch with Wine
Top hotels in Santo Spirito
Hotel Horto Convento
Very nice. Good area. Close to Arno and sites Excellent staff !!
Reviewed on 10 May 2026
Palazzo Mannaioni Suites
Amazing staff! We loved our stay
Reviewed on 9 May 2026
La Torre Del Cestello
Very convenient location, within walking distance of everything. Clean and spacious room with stunning view of the river. Very helpful staff.
Reviewed on 1 May 2026
Palazzo Oliveto
Could be cleaner and more comfortable
Reviewed on 6 May 2026
Foresteria Valdese di Firenze - Casa per Ferie
The staff were really nice and accommodating with a really late check-in. The location was very convenient and the room was clean and very comfortable. There is a fantastic corner café that we visited daily and a last Sunday of the month farmers market that we stumbled upon and loved the goat yogurt ...
Reviewed on 9 May 2026
Residenza D'Epoca Al Numero 8
great location and customer service was excellent.. little bit hard to find but ask restaurant on same street and they will tell you where it is exactly.
Reviewed on 25 Apr 2026
Other neighbourhoods around Santo Spirito
San Frediano
San Frediano is known for its stunning river views, and you can plan a trip to Piazza Santo Spirito and Boboli Gardens while you're in town.
Oltrarno
Oltrarno is a destination visitors seek out for its fascinating museums, picturesque gardens and beautiful river views. You might also want to check out attractions like Pitti Palace or Pitti Vintage while you're exploring the neighbourhood.
Santa Maria Novella
Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.
San Giovanni
If you're spending some time in San Giovanni, Uffizi Gallery and Cathedral of Santa Maria del Fiore are top sights worth seeing.
Historic Centre of Florence
Known for its fascinating museums, stunning cathedral and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Cathedral of Santa Maria del Fiore and Uffizi Gallery are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.
Duomo
Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Cathedral of Santa Maria del Fiore or Uffizi Gallery while you're exploring the neighbourhood.
