Santo Spirito Travel Guide
Florence





Visit Santo Spirito
Stay near popular Santo Spirito attractions
Things to do

Florence: Pasta Cooking Class with Unlimited Wine

Uffizi & Accademia Timed Entry: Small Group Duomo Walking Tour

Best of Florence Tour with David at Accademia & Duomo (with VIP option)

Tuscany Experience In Pisa, Siena, San Gimignano & Chianti

Florence David Tour: Michelangelo, Donatello & 48h Art Pass

Florence Vespa Tour: Tuscan Hills, Food and Chianti Wine
Top hotels in Santo Spirito

Hotel Horto Convento
"Everybody on staff was extremely helpful!"
Reviewed on 29 Aug 2026

La Torre Del Cestello
"The room was very specious and clean. AC was amazing and worked great. Perfect location too"
Reviewed on 29 Aug 2026

UNA Hotels Vittoria Firenze

Casa Santo Nome di Gesù
"Beautiful hotel in great location. Staff really helpful with local knowledge. Communal fridge available at reception, which was great for storing drinks."
Reviewed on 27 Aug 2026

Palazzo Mannaioni Suites
"Staff is very friendly and the location is close to everything."
Reviewed on 30 Aug 2026

Foresteria Valdese di Firenze - Casa per Ferie
"liked the location and the sensible modernizations - had a nice spacious and comfortable room. Appreciated the air conditioning and friendly staff - plumbing could have been better. Thankfully, there was a lift to our 2nd floor guestroom. The food was pretty good for bulk catering."
Reviewed on 30 Aug 2026
Where to stay in Santo Spirito

Historic Centre of Florence
Cathedral of Santa Maria del Fiore and Piazza di Santa Maria Novella are a few top attractions in Historic Centre of Florence. Hop around the city on the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop and check out the area's fascinating museums, stunning cathedral and stunning river views.

Duomo
Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Piazza del Duomo or Piazza di Santa Maria Novella while you're exploring the neighbourhood.

Santa Maria Novella
Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

San Giovanni
If you're spending some time in San Giovanni, Cathedral of Santa Maria del Fiore and Piazza della Repubblica are top sights worth seeing.

Santa Croce
Santa Croce is known for its interesting museums, and you can plan a trip to Basilica of Santa Croce and Piazza Santa Croce while you're in town.























