Search Hotels in South Main, Houston
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Our top choices for South Main hotels
1. Candlewood Suites Houston Medical Center by IHG
Candlewood Suites Houston Medical Center by IHGSouth Main
7.4 out of 10, Good, (888 reviews)
"This place had"
Marvin
The price is Rp1.087.088
Rp1.271.892 total
includes taxes & fees
2 Aug - 3 Aug
2. Wyndham Houston near NRG Park/Medical Center
Wyndham Houston near NRG Park/Medical CenterSouth Main
7.0 out of 10, Good, (1,360 reviews)
"Room was clean and the staff was very nice."
Juan
The price is Rp1.541.206
Rp1.803.211 total
includes taxes & fees
3 Aug - 4 Aug
3. Quality Inn & Suites NRG Park - Medical Center
Quality Inn & Suites NRG Park - Medical CenterSouth Main
6.6 out of 10, (1,006 reviews)
"convenient to medical center"
Mike
The price is Rp1.051.067
Rp1.229.750 total
includes taxes & fees
19 Aug - 20 Aug
4. Comfort Suites Houston near Medical Center- NRG Stadium
Comfort Suites Houston near Medical Center- NRG StadiumSouth Main
8.8 out of 10, Excellent, (1,001 reviews)
"Very good all around. Very close to the stadium."
marty
The price is Rp1.572.604
Rp1.839.948 total
includes taxes & fees
21 Aug - 22 Aug
5. Wingate Houston near NRG Park/Medical Center
Wingate Houston near NRG Park/Medical CenterSouth Main
6.6 out of 10, (1,001 reviews)
The price is Rp1.508.052
Rp1.764.420 total
includes taxes & fees
23 Jul - 24 Jul
6. Blossom Hotel Houston, Curio Collection by Hilton
Blossom Hotel Houston, Curio Collection by HiltonTexas Medical Center, 3.5 km from South Main
9.0 out of 10, Wonderful, (3,844 reviews)
"Everything was perfect hotel was so nice & very clean"
Taishiana
The price is Rp2.512.326
Rp2.939.420 total
includes taxes & fees
21 Aug - 22 Aug
7. Hyatt Place Houston Medical Center
Hyatt Place Houston Medical CenterTexas Medical Center, 3.1 km from South Main
9.2 out of 10, Wonderful, (2,602 reviews)
"Clean room, great breakfast and friendly staff."
Sonya
The price is Rp2.264.018
Rp2.662.940 total
includes taxes & fees
28 Jul - 29 Jul
8. Hotel Ylem
Hotel Ylem2.3 km from South Main
8.4 out of 10, Very good, (1,531 reviews)
"Nice stay and great staff"
Alelia
The price is Rp1.448.763
Rp1.784.570 total
includes taxes & fees
26 Jul - 27 Jul
9. Hyatt House Houston Medical Center
Hyatt House Houston Medical CenterTexas Medical Center, 3.1 km from South Main
9.2 out of 10, Wonderful, (1,267 reviews)
"Always very friendly and accommodating. Superior transportation support to and from hotel. Excellent breakfast"
Theresa
The price is Rp2.174.621
Rp2.557.790 total
includes taxes & fees
28 Jul - 29 Jul
10. The Westin Houston Medical Center/Museum District
The Westin Houston Medical Center/Museum DistrictTexas Medical Center, 4.4 km from South Main
9.2 out of 10, Wonderful, (1,164 reviews)
"The customer service is amazing from the valet to the front desk"
Tanasia
The price is Rp3.052.955
Rp3.800.014 total
includes taxes & fees
2 Aug - 3 Aug
11. Drury Inn & Suites Houston Near the Galleria
Drury Inn & Suites Houston Near the GalleriaThe Galleria, 9.4 km from South Main
9.4 out of 10, Exceptional, (1,483 reviews)
"Staff was so nice! The happy hour was great as well and we were really happy with the property."
Angela
The price is Rp1.684.395
Rp1.970.742 total
includes taxes & fees
3 Aug - 4 Aug
12. DoubleTree by Hilton Hotel Houston - Greenway Plaza
DoubleTree by Hilton Hotel Houston - Greenway Plaza6.6 km from South Main
8.4 out of 10, Very good, (1,736 reviews)
"Excellent place to stay with family"
Fahad
The price is Rp1.799.825
Rp2.105.796 total
includes taxes & fees
26 Jul - 27 Jul
13. Best Western Plus Pearland/Houston Medical Center Hotel
Best Western Plus Pearland/Houston Medical Center HotelSoutheast Houston, 10.2 km from South Main
9.4 out of 10, Exceptional, (359 reviews)
"Clean quiet rooms nice breakfast great staff"
Keitha
The price is Rp1.702.495
Rp1.991.918 total
includes taxes & fees
22 Jul - 23 Jul
14. Crowne Plaza Houston Med Ctr-Galleria Area by IHG
Crowne Plaza Houston Med Ctr-Galleria Area by IHG6.5 km from South Main
7.8 out of 10, Good, (1,543 reviews)
"The kitchen staff was wonderful and one of the nicest breakfast I've had at any hotel!"
Christy
The price is Rp1.120.600
Rp1.311.103 total
includes taxes & fees
16 Aug - 17 Aug
15. Studio 6 Houston, TX – Pearland/Medical Center
Studio 6 Houston, TX – Pearland/Medical CenterSoutheast Houston, 12.9 km from South Main
9.2 out of 10, Wonderful, (164 reviews)
"Clean room & nice location"
Andres
The price is Rp1.021.421
Rp1.194.978 total
includes taxes & fees
31 Jul - 1 Aug
16. Sonesta ES Suites Houston Galleria
Sonesta ES Suites Houston GalleriaThe Galleria, 8.4 km from South Main
8.4 out of 10, Very good, (1,334 reviews)
"The hotel is well located and very comfortable"
Jorge Luis
The price is Rp1.660.381
Rp1.942.636 total
includes taxes & fees
27 Jul - 28 Jul
17. Best Western Plus Downtown Inn & Suites
Best Western Plus Downtown Inn & Suites10.2 km from South Main
9.2 out of 10, Wonderful, (1,112 reviews)
"Staff was great, room clean, good location!"
John
The price is Rp2.116.649
Rp2.476.479 total
includes taxes & fees
11 Aug - 12 Aug
18. Homewood Suites by Hilton Houston Memorial
Homewood Suites by Hilton Houston Memorial16.4 km from South Main
9.6 out of 10, Exceptional, (1,006 reviews)
"Excellent for families. Clean and helpful staff."
Anup Dharia
The price is Rp1.690.846
Rp1.978.290 total
includes taxes & fees
9 Aug - 10 Aug
19. Hyatt Place Houston/Galleria
Hyatt Place Houston/Galleria8.7 km from South Main
8.8 out of 10, Excellent, (1,547 reviews)
"Excellent stay!!!"
Loukisha
The price is Rp1.812.748
Rp2.132.761 total
includes taxes & fees
7 Aug - 8 Aug
20. Hyatt Place Houston/Sugar Land
Hyatt Place Houston/Sugar Land21.4 km from South Main
8.8 out of 10, Excellent, (1,928 reviews)
"Perfect stay , everything was as expected and smelled amazing"
Raul
The price is Rp2.277.759
Rp2.619.423 total
includes taxes & fees
23 Jul - 24 Jul
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare popular hotels in South Main
Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
 Comfort Suites Houston near Medical Center- NRG Stadium | 8.8 Excellent 1,001 reviews | View | ||||||
 Candlewood Suites Houston Medical Center by IHG | 7.4 Good 888 reviews | View | ||||||
 Wyndham Houston near NRG Park/Medical Center | 7.0 Good 1,360 reviews | View | ||||||
 Quality Inn & Suites NRG Park - Medical Center | 6.6 1,006 reviews | View | ||||||
 Wingate Houston near NRG Park/Medical Center | 6.6 1,001 reviews | View |
Where to stay in South Main
Find the best South Main areas for the activities you enjoy most.
Downtown Houston
Tour the beautiful green spaces, buzzing theater district and professional sports arenas nestled beneath a dramatic cityscape of gleaming skyscrapers.
The Galleria
Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.
Texas Medical Center
Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.
Montrose
Unique features of Montrose include the theatres and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.
Photo by George Zimzores
Open Photo by George Zimzores
Houston Central Business District
If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.
Top South Main Hotel Reviews
Blossom Hotel Houston, Curio Collection by Hilton
10/10 Excellent
