Search Hotels in South Main, Houston
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Our top choices for South Main hotels
1. Wyndham Houston at Reliant Park & Medical Center
Wyndham Houston at Reliant Park & Medical CenterSouth Main
7.2 out of 10, Good, (1,407 reviews)
"Staff friendly rooms nice and clean."
Miguel
The price is Rp1.659.230
Rp1.941.299 total
includes taxes & fees
14 Sept - 15 Sept
2. Candlewood Suites Houston Medical Center by IHG
Candlewood Suites Houston Medical Center by IHGSouth Main
7.4 out of 10, Good, (896 reviews)
"Great amenities!"
Michelle
The price is Rp1.852.410
Rp2.167.320 total
includes taxes & fees
18 Sept - 19 Sept
3. Comfort Suites Houston near Medical Center- NRG Stadium
Comfort Suites Houston near Medical Center- NRG StadiumSouth Main
8.8 out of 10, Excellent, (1,005 reviews)
"Great Staff, room and location!"
chris
The price is Rp1.764.200
Rp2.064.114 total
includes taxes & fees
7 Sept - 8 Sept
4. Quality Inn & Suites NRG Park - Medical Center
Quality Inn & Suites NRG Park - Medical CenterSouth Main
6.6 out of 10, (1,002 reviews)
"Regular aceptable ."
Oscar
The price is Rp1.161.373
Rp1.358.806 total
includes taxes & fees
6 Oct - 7 Oct
5. Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG
Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG1.4 km from South Main
9.4 out of 10, Exceptional, (1,002 reviews)
"I’ll stay again"
Kevin
The price is Rp2.086.122
Rp2.455.084 total
includes taxes & fees
8 Sept - 9 Sept
6. Hyatt Place Houston Medical Center
Hyatt Place Houston Medical CenterTexas Medical Center, 3.1 km from South Main
9.2 out of 10, Wonderful, (2,652 reviews)
"Lovely stay!"
Lamarr
The price is Rp2.207.014
Rp2.595.892 total
includes taxes & fees
7 Sept - 8 Sept
7. Hyatt House Houston Medical Center
Hyatt House Houston Medical CenterTexas Medical Center, 3.1 km from South Main
9.2 out of 10, Wonderful, (1,283 reviews)
"Great lodging, staff, breakfast, and shuttle service to MD Anderson."
ALFRED
The price is Rp2.228.771
Rp2.621.482 total
includes taxes & fees
11 Sept - 12 Sept
8. Courtyard By Marriott Houston Medical Center Reliant Park
Courtyard By Marriott Houston Medical Center Reliant Park2.7 km from South Main
8.6 out of 10, Excellent, (1,003 reviews)
"Great Hotel!"
Jorge
The price is Rp1.893.421
Rp2.238.316 total
includes taxes & fees
27 Sept - 28 Sept
9. Blossom Hotel Houston, Curio Collection by Hilton
Blossom Hotel Houston, Curio Collection by HiltonTexas Medical Center, 3.5 km from South Main
9.0 out of 10, Wonderful, (3,902 reviews)
"I loved staying here!"
Kamauri
The price is Rp2.523.177
Rp2.961.857 total
includes taxes & fees
7 Sept - 8 Sept
10. Hotel Ylem
Hotel Ylem2.3 km from South Main
8.4 out of 10, Very good, (1,561 reviews)
"We found a clean room, all amenities, tv and
a/c
The breakfast is so good and fresh"
GUSTAVO
The price is Rp1.113.431
Rp1.390.924 total
includes taxes & fees
15 Sept - 16 Sept
11. The Westin Houston Medical Center/Museum District
The Westin Houston Medical Center/Museum DistrictTexas Medical Center, 4.4 km from South Main
9.2 out of 10, Wonderful, (1,197 reviews)
"Great place to stay"
Kevin
The price is Rp2.280.846
Rp2.838.970 total
includes taxes & fees
7 Sept - 8 Sept
12. Best Western Plus Downtown Inn & Suites
Best Western Plus Downtown Inn & Suites10.2 km from South Main
9.2 out of 10, Wonderful, (1,125 reviews)
"Clean rooms, friendly staff, and great breakfast."
ROMAN
The price is Rp2.050.883
Rp2.399.532 total
includes taxes & fees
11 Sept - 12 Sept
13. The Moran CITYCENTRE
The Moran CITYCENTRE18.3 km from South Main
9.0 out of 10, Wonderful, (1,172 reviews)
"we had a great stay!"
Jayce
The price is Rp3.150.813
Rp4.212.005 total
includes taxes & fees
6 Sept - 7 Sept
14. Hilton Houston Plaza/Medical Center
Hilton Houston Plaza/Medical CenterTexas Medical Center, 4.4 km from South Main
8.4 out of 10, Very good, (2,135 reviews)
"Our stay was great"
Cindy
The price is Rp1.376.076
Rp1.630.473 total
includes taxes & fees
7 Sept - 8 Sept
15. The Chifley Houston, Tapestry Collection by Hilton
The Chifley Houston, Tapestry Collection by HiltonThe Galleria, 8.7 km from South Main
9.2 out of 10, Wonderful, (1,350 reviews)
"This is a great hotel in the perfect location and close to everything."
Ronald
The price is Rp2.015.052
Rp2.357.612 total
includes taxes & fees
11 Sept - 12 Sept
16. Hyatt Place Houston/Galleria
Hyatt Place Houston/Galleria8.7 km from South Main
8.8 out of 10, Excellent, (1,601 reviews)
"A good stay overall"
Adaobi
The price is Rp1.887.694
Rp2.220.246 total
includes taxes & fees
12 Sept - 13 Sept
17. Embassy Suites by Hilton Houston Energy Corridor
Embassy Suites by Hilton Houston Energy Corridor21 km from South Main
9.2 out of 10, Wonderful, (1,002 reviews)
"Breakfast was wonderful…the staff was kind and accommodating"
Angela
The price is Rp2.589.493
Rp3.029.707 total
includes taxes & fees
11 Sept - 12 Sept
18. Crowne Plaza Houston Med Ctr-Galleria Area by IHG
Crowne Plaza Houston Med Ctr-Galleria Area by IHGGreenway Plaza-Upper Kirby, 6.5 km from South Main
7.8 out of 10, Good, (1,612 reviews)
"Stay was nice’! Will stay again"
Lanita
The price is Rp1.109.682
Rp1.298.275 total
includes taxes & fees
7 Sept - 8 Sept
19. Drury Inn & Suites Houston Near the Galleria
Drury Inn & Suites Houston Near the GalleriaThe Galleria, 9.4 km from South Main
9.4 out of 10, Exceptional, (1,552 reviews)
"Great location, wonderful breakfast"
Andrei
The price is Rp1.658.172
Rp1.940.062 total
includes taxes & fees
20 Sept - 21 Sept
20. Quality Suites Houston Hobby Airport
Quality Suites Houston Hobby AirportSoutheast Houston, 13.3 km from South Main
8.4 out of 10, Very good, (1,274 reviews)
"Great place to stay"
Jason
The price is Rp1.237.586
Rp1.447.975 total
includes taxes & fees
29 Sept - 30 Sept
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in South Main
Find the best South Main areas for the activities you enjoy most.
Downtown Houston
Tour the beautiful green spaces, buzzing theater district and professional sports arenas nestled beneath a dramatic cityscape of gleaming skyscrapers.
The Galleria
Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Gerald D. Hines Waterwall Park.
Texas Medical Center
Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.
Montrose
Unique features of Montrose include the theatres and museums. Make a stop by Menil Collection or Rothko Chapel while you're exploring the area.
Photo by George Zimzores
Open Photo by George Zimzores
Houston Central Business District
If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.
