Uptown Travel Guide

Collinsville

A tall water tower with a red and white striped top, surrounded by trees and a clear blue sky.
A tall, cylindrical structure with a red and white striped pattern and a label reading "Brock's Old Original Catsup."

Stay near popular Uptown attractions

Things to do


Top hotels in Uptown

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
The price is Rp2.376.520 per night from 4 Sept to 5 Sept
Rp2.376.520
Rp2.802.607 total
4 Sept - 5 Sept
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 3 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
Hyatt Regency St. Louis at The Arch
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
The price is Rp1.411.554 per night from 20 Sept to 21 Sept
Rp1.411.554
Rp1.647.820 total
20 Sept - 21 Sept
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the pool ...
Clayton Plaza Hotel & Extended Stay
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
The price is Rp2.711.289 per night from 9 Sept to 10 Sept
Rp2.711.289
Rp3.170.283 total
9 Sept - 10 Sept
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and 2 hot tubs. Our guests praise the breakfast and the pool in their reviews. ...
Drury Plaza Hotel St. Louis at the Arch
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

4 out of 5
3550 Samuel Sheppard Drive St. Louis MO
The price is Rp1.902.244 per night from 9 Sept to 10 Sept
Rp1.902.244
Rp2.243.298 total
9 Sept - 10 Sept
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, a rooftop terrace and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.8/10 Excellent! (1,147 reviews)
"Overall, the hotel was very nice. The restaurant and staff super nice. The hotel had a night club upstairs so if that’s your thing this is the spot for you."

Reviewed on 1 Sept 2026

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

3.5 out of 5
333 Washington Ave St. Louis MO
The price is Rp2.165.274 per night from 7 Sept to 8 Sept
Rp2.165.274
Rp2.531.832 total
7 Sept - 8 Sept
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,385 reviews)
"Raven at the front desk was wonerful and very friendly and helpful!!"

Reviewed on 1 Sept 2026

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
The price is Rp2.545.765 per night from 27 Sept to 28 Sept
Rp2.545.765
Rp3.065.348 total
27 Sept - 28 Sept
includes taxes & fees
Stay at this luxury hotel in St. Louis. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the pool and the restaurant in their reviews. ...
21C Museum Hotel St Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Uptown

Find the best Uptown areas for the activities you enjoy most.

Eastport

While visiting Eastport, you might make a stop by sights like Gateway Conference Center and Splash City Family Waterpark.

Mulberry Hills

Though Mulberry Hills may not have many top sights, you can venture to the surrounding area to see attractions like Gateway Conference Center and Stonewolf Golf Course.

Historic Downtown Collinsville

Though Historic Downtown Collinsville may not have many top sights, you can venture to the surrounding area to see attractions like Gateway Conference Center and Splash City Family Waterpark.



Uptown Travel Guide