Popular places to visit

Multiplaza Pacific Mall
During your trip to Panama City, you can search for that perfect souvenir at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.

Cinta Costera
Explore the great outdoors at Cinta Costera, a lovely green space in Panama City. While you're in the area, stroll along the seaside.

Avenida Balboa
You can browse for the perfect souvenirs at Avenida Balboa during your stay in Panama City. While you're in the area, wander around the natural setting.

Fuerte Amador Resort & Marina
Explore the waterfront in Ancon with a trip to Fuerte Amador Resort & Marina. Visit the shops and top-notch restaurants in this vibrant area.

Miraflores Locks
Learn about the local history of Ancon when you spend time at Miraflores Locks. Visit the shops and casinos in this vibrant area.

Calle 50
You can find out about the history of Panama City when you stop by Calle 50. Discover the area's casinos or seek out its local tours.
Things to do

City Sightseeing Panama City Hop-On Hop-Off Bus Tour

Panama City: All-Inclusive Catamaran Cruise to Taboga Island

Half day of Panama city and canal tour: shared and private

Boat tour in the Panama Canal to Monkeys and sloths islands

Panama City: Poin Full Package Experience

Private or Small Group Panama Canal & City Half-Day Tour
Top hotels in Santa Ana

Casco View Apartments
Room was clean large and great to have kitchen and laundry in the unit. The pool is small and not really a lounging area. Overall it was super loud, dogs barking, alarms going off and immediate area a little sketch
Reviewed on 27 Oct 2025

Hotel Riu Plaza Panama
Todo muy bien, buena ubicado, limpieza y muy buena atencion, buen desayuno, solo los tragos preparados de la piscina de poca calidad. Gracias por todos los dias maravillosos.
Reviewed on 27 Nov 2025

Crowne Plaza Panama Airport by IHG
Llegué tarde en la noche y me fui temprano. No pude disfrutar de ningún amenities.
Reviewed on 25 Nov 2025

Las Americas Golden Tower Panama
Room price is reasonable, location is good!
Reviewed on 24 Nov 2025

Sheraton Grand Panama
Excelente atención y servicio La cuna de bebé era de material como fierro, insegura para bebés que ya se paran un poco El área de juegos de niños siempre mojada y no tenía protección solar podría adecuarse mejor
Reviewed on 1 Nov 2025

Megapolis Hotel Panamá
Every thing was perfect. Great hotel..! recommended 100%
Reviewed on 1 Dec 2025
Other neighbourhoods around Santa Ana

Casco Viejo
Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

San Felipe
While visiting San Felipe, you might make a stop by sights like Independence Square and Interoceanic Canal Museum.

El Chorrillo
While El Chorrillo isn't home to many top sights, Albrook Shopping Mall and Ancon Hill are some notable places to visit nearby.

Calidonia
Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Estación Lotería or Santo Tomas Station to explore sights like Cinta Costera.

Balboa
The restaurants and shopping are just a few features travellers like about Balboa. If you want to do some sightseeing nearby, Albrook Shopping Mall and Ancon Hill are a few top places to visit.

Marbella
You'll enjoy the restaurants and parks in Marbella. You might want to make time for a stop at Avenida Balboa or Cinta Costera.

