Santa Ana Travel Guide

Panama City

Plaza Santa Ana, Panama Casco Viejo
Plaza Santa Ana, Panama Casco Viejo
View from the fish market
go there and eat fresh and yummy fish in all variations

Popular places to visit

Things to do


Top hotels in Santa Ana

Casco View Apartments

Casco View Apartments

3.5 out of 5
C. 16 Oeste Panama City Provincia de Panamá
Stay at this business-friendly condo in Panama City. Enjoy free Wi-Fi, a 24-hour front desk and airport pick-up service (surcharge). Popular attractions Cinta ...
9.2/10 Wonderful! (75 reviews)
The room was spotless and the decor was beautiful. The location was very convenient and the staff was friendly, in particular Marciello. The only downsides were that there was no hot water in the shower and the air conditioning vented onto the deck, making it really hot to sit on the deck.

Reviewed on 22 Feb 2026

Casco View Apartments
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
The price is Rp2.386.356 per night from 8 Mar to 9 Mar
Rp2.386.356
Rp2.624.992 total
8 Mar - 9 Mar
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and 3 restaurants. Our guests praise the breakfast and the pool in their reviews. ...
9/10 Wonderful! (5,070 reviews)
Good location with the ability to walk to near by shops and restaurant. The room was clean. We didnt have any complaints.

Reviewed on 4 Mar 2026

Hotel Riu Plaza Panama
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
The price is Rp2.344.652 per night from 2 Apr to 3 Apr
Rp2.344.652
Rp2.579.117 total
2 Apr - 3 Apr
includes taxes & fees
Stay at this family-friendly hotel in Tocumen. Enjoy free Wi-Fi, breakfast (surcharge) and a free airport shuttle. Our guests praise the breakfast and the pool ...
8.6/10 Excellent! (2,467 reviews)
We stayed one night on a layover from Atlanta to Manta Ecuador. The shuttle picked us up from the airport without problems. The hotel was clean and modern. The staff was friendly. The prices for food and snacks were exorbitant and out of line with the cost of items in Panama, however,

Reviewed on 4 Mar 2026

Crowne Plaza Panama Airport by IHG
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111 Panama City Panama
The price is Rp1.822.176 per night from 23 Mar to 24 Mar
Rp1.822.176
Rp2.004.394 total
23 Mar - 24 Mar
includes taxes & fees
Stay at this spa hotel in Panama City. Enjoy free breakfast, free parking and a full-service spa. Our guests praise the helpful staff in their reviews. Popular ...
7.8/10 Good! (1,011 reviews)
Was clean but very noisy pool area on weekends

Reviewed on 3 Mar 2026

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
W Panama

W Panama

5 out of 5
Calle Aquilino de la Guardia & Calle 50 Panama City
The price is Rp3.360.902 per night from 31 Mar to 1 Apr
Rp3.360.902
Rp3.696.992 total
31 Mar - 1 Apr
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy 2 restaurants, 3 hot tubs and 2 bars/lounges. Our guests praise the helpful staff in their reviews. Popular attractions ...
9/10 Wonderful! (1,010 reviews)
Great location, friendly staff, clean room, modern facilities

Reviewed on 3 Mar 2026

W Panama
Waldorf Astoria Panama

Waldorf Astoria Panama

5 out of 5
47th St. & Uruguay Street Panama City Panama
The price is Rp3.305.791 per night from 4 Apr to 5 Apr
Rp3.305.791
Rp3.636.370 total
4 Apr - 5 Apr
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy free Wi-Fi, a full-service spa and 2 restaurants. Our guests praise the helpful staff in their reviews. Popular ...
9/10 Wonderful! (1,001 reviews)
The hotel was wonderful. The entire hotel was clean, staff welcoming especially security employee Flash. The breakfast buffet was great and it was so nice that Divney the receptionist remembered our names each day. My overall stay was great and I would highly recommend this hotel to anyone visiting ...

Reviewed on 23 Feb 2026

Waldorf Astoria Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Santa Ana

View of the Panama City Old Town

Casco Viejo

3.5/5(3 area reviews)

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Casco Viejo
Balcony of a colonial house, Casco Viejo, Panama City, Panama, Central America

San Felipe

While visiting San Felipe, you might make a stop by sights like Independence Square and Interoceanic Canal Museum.

San Felipe
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El Chorrillo

While El Chorrillo isn't home to many top sights, Maracana Stadium and Flag of Cerro Ancón are some notable places to visit nearby.

El Chorrillo
The skyline at Panama City, Panama. There are some nice walkways along the waterfront.

Calidonia

Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Estación Lotería or Santo Tomas Station to explore sights like Cinta Costera.

Calidonia
The buses of Panama.

Balboa

The restaurants and shopping are just a few features travellers like about Balboa. If you want to do some sightseeing nearby, Flag of Cerro Ancón and Bridge of the Americas are a few top places to visit.

Balboa
Old and traditional Yatch Club at Cinta Costera, Panama City, Panama.

Marbella

You'll enjoy the restaurants and parks in Marbella. You might want to make time for a stop at Avenida Balboa or Cinta Costera.

Marbella


Santa Ana Travel Guide