Search Hotels Near Key West National Wildlife Refuge, Key West

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
22 Dec - 23 Dec
Tomorrow
23 Dec - 24 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Key West National Wildlife Refuge hotels

Queen Deluxe ADA | Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds
Almond Tree Inn Hotel - Adults Only

Almond Tree Inn Hotel - Adults Only

Almond Tree Inn Hotel - Adults Only
3.5 star property
Downtown Key West, 11.8 km from Key West National Wildlife Refuge
10.0 out of 10, Exceptional, (1002)
"Great location, spotless rooms, attentive and friendly staff, great value."
United States
David
The price is Rp6.061.825
Rp6.819.553 total
includes taxes & fees
23 Dec - 24 Dec
Almond Tree Inn Hotel - Adults Only
Queen with Pool View | Minibar, in-room safe, individually decorated, individually furnished
Simonton Court Historic Inn & Cottages

Simonton Court Historic Inn & Cottages

Simonton Court Historic Inn & Cottages
2.5 star property
Historic Seaport, 11.4 km from Key West National Wildlife Refuge
9.8 out of 10, Exceptional, (883)
"The staff was really nice"
United States
doug
The price is Rp5.510.750
Rp6.199.594 total
includes taxes & fees
23 Dec - 24 Dec
Simonton Court Historic Inn & Cottages
Front of property
L'Habitation Guest House

L'Habitation Guest House

L'Habitation Guest House
2.5 star property
Historic Seaport, 11.2 km from Key West National Wildlife Refuge
9.4 out of 10, Exceptional, (924)
"A great no hassle stay."
United States
Gary
The price is Rp4.251.485
Rp4.782.963 total
includes taxes & fees
5 Jan - 6 Jan 2026
L'Habitation Guest House
Property grounds
Duval House

Duval House

Duval House
3.0 star property
Downtown Key West, 11.7 km from Key West National Wildlife Refuge
9.4 out of 10, Exceptional, (1001)
"I loved this place the location was absolutely perfect "
United States
Frank
The price is Rp3.323.705
Rp4.099.293 total
includes taxes & fees
23 Dec - 24 Dec
Duval House
Front of property – evening/night
Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West
4.0 star property
Old Town Key West, 11 km from Key West National Wildlife Refuge
9.2 out of 10, Wonderful, (1026)
"Our stay was great!"
United States
Richard
The price is Rp6.683.250
Rp8.178.355 total
includes taxes & fees
23 Dec - 24 Dec
Opal Key Resort & Marina, Key West
Outdoor pool, pool loungers
Ocean Key Resort - A Noble House Resort

Ocean Key Resort - A Noble House Resort

Ocean Key Resort - A Noble House Resort
4.0 star property
Historic Seaport, 11 km from Key West National Wildlife Refuge
9.2 out of 10, Wonderful, (1006)
"Clean and spacious room, staff "
United States
Parikshit
The price is Rp8.709.330
Rp11.098.300 total
includes taxes & fees
5 Jan - 6 Jan 2026
Ocean Key Resort - A Noble House Resort
Property grounds
Orchid Key Inn - Adults Only

Orchid Key Inn - Adults Only

Orchid Key Inn - Adults Only
3.5 star property
Uptown - Upper Duval, 11.8 km from Key West National Wildlife Refuge
9.8 out of 10, Exceptional, (1001)
"Staff awesome, good breakfast great location"
United States
Carin helen
The price is Rp6.061.825
Rp6.819.553 total
includes taxes & fees
23 Dec - 24 Dec
Orchid Key Inn - Adults Only
Front of property
Key West Villas

Key West Villas

Key West Villas
3.5 star property
Downtown Key West, 11.6 km from Key West National Wildlife Refuge
9.8 out of 10, Exceptional, (247)
"Awsome staff great location "
United States
Jeffrey
Key West Villas
Veranda Room | Terrace/patio
The Conch House Heritage Inn

The Conch House Heritage Inn

The Conch House Heritage Inn
3.5 star property
Old Town Key West, 12 km from Key West National Wildlife Refuge
9.8 out of 10, Exceptional, (145)
"Fantastic location "
United States
ANDREW
The price is Rp5.752.620
Rp6.471.698 total
includes taxes & fees
4 Jan - 5 Jan 2026
The Conch House Heritage Inn
Exterior
Coco Plum Inn

Coco Plum Inn

Coco Plum Inn
3.0 star property
Downtown Key West, 11.4 km from Key West National Wildlife Refuge
9.6 out of 10, Exceptional, (468)
"Love the place convenient, clean and really nice"
United States
Matthew
The price is Rp5.261.175
Rp5.918.948 total
includes taxes & fees
23 Dec - 24 Dec
Coco Plum Inn
11 Gecko's Garden - Adults Only | Premium bedding, pillow-top beds, individually decorated
Tropical Inn

Tropical Inn

Tropical Inn
3.5 star property
Downtown Key West, 11.7 km from Key West National Wildlife Refuge
9.6 out of 10, Exceptional, (364)
"Nice place to stay "
United States
yulio
The price is Rp4.111.120
Rp5.043.760 total
includes taxes & fees
23 Dec - 24 Dec
Tropical Inn
Private beach, white sand, sun-loungers, beach umbrellas
Pier House Resort & Spa

Pier House Resort & Spa

Pier House Resort & Spa
4.0 star property
Historic Seaport, 11 km from Key West National Wildlife Refuge
9.0 out of 10, Wonderful, (1007)
"Lovely hotel, great room and ideal location."
United States
Donald
The price is Rp6.552.600
Rp8.464.614 total
includes taxes & fees
23 Dec - 24 Dec
Pier House Resort & Spa
Cigar House King Suite w/ Poolside porch | Balcony view
Island City House Hotel

Island City House Hotel

Island City House Hotel
3.0 star property
Historic Seaport, 11.7 km from Key West National Wildlife Refuge
9.6 out of 10, Exceptional, (1001)
"Excellent stay"
United States
Emily Barbara
The price is Rp5.728.500
Rp6.444.563 total
includes taxes & fees
23 Dec - 24 Dec
Island City House Hotel
Courtyard
The Grand Guesthouse

The Grand Guesthouse

The Grand Guesthouse
2.5 star property
Old Town Key West, 12.5 km from Key West National Wildlife Refuge
9.6 out of 10, Exceptional, (1001)
"Great stay"
United States
Ginger
The price is Rp5.010.176
Rp6.055.198 total
includes taxes & fees
23 Dec - 24 Dec
The Grand Guesthouse
Premium bedding, iron/ironing board, free WiFi, bed sheets
Weatherstation Inn

Weatherstation Inn

Weatherstation Inn
2.5 star property
Truman Annex, 11 km from Key West National Wildlife Refuge
9.4 out of 10, Exceptional, (996)
"Wonderful property safe neighborhood convenient to all activities would stay here again."
United States
William
The price is Rp5.008.250
Rp5.634.281 total
includes taxes & fees
23 Dec - 24 Dec
Weatherstation Inn
Exterior
La Concha Key West, Autograph Collection

La Concha Key West, Autograph Collection

La Concha Key West, Autograph Collection
4.0 star property
Historic Seaport, 11.3 km from Key West National Wildlife Refuge
9.0 out of 10, Wonderful, (295)
"Very nice staff! Clean hotel! "
United States
Tabitha Hall
The price is Rp5.963.000
Rp7.273.688 total
includes taxes & fees
5 Jan - 6 Jan 2026
La Concha Key West, Autograph Collection
Audubon Room - Adult Exclusive | Terrace/patio
The Mermaid & Alligator

The Mermaid & Alligator

The Mermaid & Alligator
3.5 star property
Old Town Key West, 12.1 km from Key West National Wildlife Refuge
9.8 out of 10, Exceptional, (275)
"Great place"
United States
Carol A
The Mermaid & Alligator
Exterior
The Garden House

The Garden House

The Garden House
3.0 star property
Historic Seaport, 11.5 km from Key West National Wildlife Refuge
9.2 out of 10, Wonderful, (668)
"It a small convenient location and walkable to great areas. "
United States
Manuel
The price is Rp3.695.553
Rp4.517.643 total
includes taxes & fees
23 Dec - 24 Dec
The Garden House
3 outdoor pools, a heated pool, pool loungers
Ambrosia Key West

Ambrosia Key West

Ambrosia Key West
3.5 star property
Old Town Key West, 11.6 km from Key West National Wildlife Refuge
9.4 out of 10, Exceptional, (1002)
"Great location and clean room. Pool was relaxing; breakfast was good!"
United States
Jennifer
The price is Rp4.684.137
Rp5.269.655 total
includes taxes & fees
23 Dec - 24 Dec
Ambrosia Key West
Lobby sitting area
Westwinds Inn

Westwinds Inn

Westwinds Inn
3.5 star property
Historic Seaport, 11.9 km from Key West National Wildlife Refuge
9.4 out of 10, Exceptional, (1002)
"Great location and loved the heated pool!"
United States
Tammy
Westwinds Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Key West National Wildlife Refuge Hotel Reviews

Hyatt Vacation Club at Sunset Harbor, Key West

Hyatt Vacation Club at Sunset Harbor, Key West

10/10 Excellent
"Great location and staff was friendly. The pool area was perfect. "
Deborah 6-night trip
Posted 2 days ago
Hyatt Vacation Club at Sunset Harbor, Key West

Hotels near other Key West National Wildlife Refuge attractions

Truman Beach

Why not spend a lazy afternoon at Truman Beach during your trip to Key West? Stroll along the seaside or discover the area's beautiful sunsets.
See properties
Fort Zachary Taylor Park, Key West. State Park in Florida, USA., Shutterstock ID 761867707, Purchase Order: SP-1891 Wave 0, Client/Licensee: Hotels.com

Fort Zachary Taylor Historic State Park

4.4/5 (1,160 reviews)
The displays of old weapons and interpretive panels in a fort at the heart of the southernmost state park in the continental U.S. provide information about the Civil War.
See properties

Frequently asked questions

What's the area like around Key West National Wildlife Refuge?
Key West National Wildlife Refuge is located in an area of Key West known for its bar scene, cycling and lively festivals. Key West is home to 2773 hotels and other accommodation options, so you can find something that's perfect for your stay.
What's the best hotel to stay close to Key West National Wildlife Refuge?
Pier House Resort & Spa is one of the top choices for your stay based on our traveller data, and this resort offers a full-service spa and a private beach. You'll find it 6.9 mi (11 km) from Key West National Wildlife Refuge. Other good options around the area include Ocean Key Resort - A Noble House Resort and Opal Key Resort & Marina, Key West.
If I need to cancel the hotel reservation for my stay near Key West National Wildlife Refuge, will I receive a refund?
Yes, the majority of room reservations are refundable if you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If you have a reservation that's non-refundable, you might still have the option to cancel and receive a refund within 24 hours of booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to view the best deals available near Key West National Wildlife Refuge.