Medical Center District Travel Guide

San Antonio

River walk in San Antonio
Tourists River Walk San Antonio Texas
Riverboat on the San Antonio River Walk, San Antonio, Texas, United States of America.
River walk in San Antonio
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Popular places to visit

Things to do


Top hotels in Medical Center District

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd San Antonio TX
The price is Rp1.568.830 per night from 24 May to 25 May
Rp1.568.830
Rp1.854.328 total
24 May - 25 May
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (3,355 reviews)
"The hotel was clean ans the breakfast was great, over all the stay was good. I did find some problems the pool had a lot of leaves, the remote for the T.V. in our room was broken and we had a hard time making it work. Since the pool was dirty I wanted to take a bath, bit the thing to close the tub ..."

Reviewed on 22 May 2026

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410 San Antonio TX
The price is Rp1.787.017 per night from 5 Jun to 6 Jun
Rp1.787.017
Rp2.123.545 total
5 Jun - 6 Jun
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy a free local area shuttle, room service and a 24-hour fitness centre. Our guests praise the helpful ...
8.6/10 Excellent! (1,059 reviews)
"While the staff was polite and attempted to accommodate us by transferring us to another room, the overall condition of both rooms did not meet the expectations of a deluxe room. The furniture showed visible wear and damage, including torn cushions, chipped finishes, and heavily worn carpet that ..."

Reviewed on 18 May 2026

San Antonio Marriott Northwest Medical Center
Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio

3 out of 5
8585 Marriott Dr San Antonio TX
The price is Rp1.636.848 per night from 7 Jun to 8 Jun
Rp1.636.848
Rp1.934.901 total
7 Jun - 8 Jun
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,000 reviews)
"When I checked for a week and payed CASH IN TOWN FOR A MILITARY EVENT AT LACKLAND AFB DRIVE 25 hours, NO ONE INFORMED ME IF I HAD TO LEAVE EARLY I NEED TO GIVE A NOTICE OR THE HOTEL WOULD RETAIN A FEE OF 129.00. It just not a way to handle playing customers of over 25 years!"

Reviewed on 8 May 2026

Courtyard by Marriott Medical Center San Antonio
Drury Plaza Hotel San Antonio Riverwalk

Drury Plaza Hotel San Antonio Riverwalk

4 out of 5
105 S Saint Marys Street San Antonio TX
The price is Rp2.473.203 per night from 31 May to 1 Jun
Rp2.473.203
Rp2.923.548 total
31 May - 1 Jun
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and 2 hot tubs. Our guests praise the breakfast and the pool in their reviews. ...
9.4/10 Exceptional! (4,650 reviews)
"Staff was friendly. The hotel was an older one but it seemed to be pretty clean. Enjoyed the happy hour."

Reviewed on 22 May 2026

Drury Plaza Hotel San Antonio Riverwalk
Menger Hotel

Menger Hotel

3.5 out of 5
204 Alamo Plaza San Antonio TX
The price is Rp1.444.277 per night from 31 May to 1 Jun
Rp1.444.277
Rp1.707.266 total
31 May - 1 Jun
includes taxes & fees
Stay at this historic hotel in San Antonio. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the pool and the bar in their reviews. ...
8.8/10 Excellent! (4,019 reviews)
"Wonderful Historic Hotel, great pool, great Location"

Reviewed on 22 May 2026

Menger Hotel
Sonesta ES Suites San Antonio Downtown Alamo Plaza

Sonesta ES Suites San Antonio Downtown Alamo Plaza

3 out of 5
425 Bonham San Antonio TX
The price is Rp2.003.438 per night from 31 May to 1 Jun
Rp2.003.438
Rp2.368.245 total
31 May - 1 Jun
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and an outdoor pool. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (2,170 reviews)
"Clean room, friendly staff and breakfast."

Reviewed on 22 May 2026

Sonesta ES Suites San Antonio Downtown Alamo Plaza
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Medical Center District

The Alamo in San Antonio, Texas

Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Convocation Center are top sights worth seeing.

Northwest Side
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Shearer Hills - Ridgeview

While visiting Shearer Hills - Ridgeview, you might make a stop by sights like North Star Mall and San Pedro Driving Range & Par 3 Course.

Shearer Hills - Ridgeview
River Walk in San Antonio, Texas

Midtown

Unique features of Midtown include the river views and bars. Make a stop by The DoSeum or San Antonio Zoo and Aquarium while you're exploring the area.

Midtown
Texas Six Flags night light,2018

La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

La Cantera District
Tobin Hill

Tobin Hill

Tobin Hill might not have many top sights, but San Antonio Museum of Art and McFarlin Tennis Center are two attractions nearby that you can check out.

Tobin Hill
Dallas Skyline Reflection on Trinity River During Sunset, Dallas, Texas.

Uptown

If you're spending some time in Uptown, Marion Koogler McNay Art Museum and Alamo Quarry Market are top sights worth seeing.

Uptown


Medical Center District Travel Guide