Medical Center District Travel Guide

San Antonio

A cityscape with a prominent tower, a large body of water, and a sunset.
A canal with colorful umbrellas and trees along the banks.
A riverside café with colorful umbrellas and tables.
A tranquil waterway flanked by lush greenery and stone pathways.
A canal with a boat, surrounded by lush greenery and a stone bridge.

Stay near popular Medical Center District attractions

Things to do


Top hotels in Medical Center District

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd San Antonio TX
The price is Rp1.566.610 per night from 8 Sept to 9 Sept
Rp1.566.610
Rp1.851.704 total
8 Sept - 9 Sept
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very good! (3,631 reviews)
"Everything everyone was very helpful..."

Reviewed on 7 Sept 2026

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center

3 out of 5
9806 Interstate Hwy 10 W San Antonio TX
The price is Rp1.587.604 per night from 13 Sept to 14 Sept
Rp1.587.604
Rp1.876.691 total
13 Sept - 14 Sept
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
Drury Inn & Suites San Antonio Northwest Medical Center
Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio

3 out of 5
8585 Marriott Dr San Antonio TX
The price is Rp1.570.138 per night from 18 Sept to 19 Sept
Rp1.570.138
Rp1.856.045 total
18 Sept - 19 Sept
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
Courtyard by Marriott Medical Center San Antonio
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410 San Antonio TX
The price is Rp1.634.531 per night from 3 Oct to 4 Oct
Rp1.634.531
Rp1.942.395 total
3 Oct - 4 Oct
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy room service, a 24-hour fitness centre and Wi-Fi (surcharge). Our guests praise the helpful staff ...
San Antonio Marriott Northwest Medical Center
Hotel Valencia Riverwalk

Hotel Valencia Riverwalk

4.5 out of 5
150 E Houston St San Antonio TX
The price is Rp2.425.599 per night from 24 Sept to 25 Sept
Rp2.425.599
Rp3.371.386 total
24 Sept - 25 Sept
includes taxes & fees
Stay at this luxury hotel in San Antonio. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the clean rooms in ...
9.4/10 Exceptional! (3,068 reviews)
"Front desk always makes people wait after knowing that check in is at 4pm and when alot of hotel let you check at 3pm or earlier but this place always makes you wait a long time"

Reviewed on 7 Sept 2026

Hotel Valencia Riverwalk
Riverwalk Plaza

Riverwalk Plaza

4 out of 5
100 Villita Street San Antonio TX
The price is Rp1.509.008 per night from 14 Sept to 15 Sept
Rp1.509.008
Rp1.783.783 total
14 Sept - 15 Sept
includes taxes & fees
Stay at this family-friendly hotel in San Antonio. Enjoy free Wi-Fi, room service and a 24-hour fitness centre. Our guests praise the restaurant and the helpful ...
8/10 Very good! (6,487 reviews)
"Great location! Close enough walk to the Alamodome!!"

Reviewed on 7 Sept 2026

Riverwalk Plaza
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Medical Center District

Find the best Medical Center District areas for the activities you enjoy most.

Downtown San Antonio

A scenic riverfront great entertainment and top sights from Alamo to Aztec Theater – discover Downtown San Antonio, a destination also famous for its historic sites.

Uptown

If you're spending some time in Uptown, Marion Koogler McNay Art Museum and Quarry Golf Club are top sights worth seeing.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Convocation Center are top sights worth seeing.

Stone Oak

Stone Oak is known for its abundant dining options, and you can plan a trip to Shops at Hardy Oak and Alta Vista at Stone Oak while you're in town.



Medical Center District Travel Guide