Otay Mesa Travel Guide

San Diego

A city skyline with high-rise buildings and a bridge over a body of water.
An aerial view of a densely populated city with a mix of residential and commercial buildings, surrounded by greenery and a clear sky.
A hillside town with a winding road, a bridge in the distance, and a river in the foreground.

Stay near popular Otay Mesa attractions

Cross Border Xpress

Cross Border Xpress is just one of the places to see in San Diego, so why not enjoy the other things to explore during your travels? Visit the shops in this family-friendly area or simply enjoy its restaurants.
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Things to do

Tijuana Urban Art Walk from San Diego

Tijuana Urban Art Walk from San Diego

Rp1.445.200
per adult
Tijuana Urban Art Walk from San Diego
Tour from San Diego to Rosarito / Portales / Puerto Nuevo Lobster

Tour of San Diego>Rosarito >Giant Christ>Puerto Nuevo Lobster

Rp1.788.435
per adult
Tour of San Diego>Rosarito >Giant Christ>Puerto Nuevo Lobster
Taco Tuesday Hop to Tijuana from San Diego

Taco Tuesday Hop to Tijuana from San Diego

Rp1.499.395
per adult
Taco Tuesday Hop to Tijuana from San Diego
Kayak on the San Diego Bay

Kayak on the San Diego Bay

Rp361.300
per adult
Kayak on the San Diego Bay
From Tijuana: Valle de Guadalupe Shared Winery Tour

From Tijuana: Valle de Guadalupe Shared Winery Tour

Rp1.499.290
per adult
100% of travellers recommend
From Tijuana: Valle de Guadalupe Shared Winery Tour
Crossing Borders: Tijuana Day Trip from San Diego

Crossing Borders: Tijuana Day Trip from San Diego

Rp1.680.045
per adult
94% of travellers recommend
Crossing Borders: Tijuana Day Trip from San Diego
See all activities in San Diego

Top hotels in Otay Mesa

Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
The price is Rp4.310.862 per night from 30 Aug to 31 Aug
Rp4.310.862
Rp5.908.846 total
30 Aug - 31 Aug
includes taxes & fees
Stay at this beach resort in San Diego. Enjoy free Wi-Fi, 5 outdoor pools and a full-service spa. Our guests praise the pool and the helpful staff in their reviews. ...
8.8/10 Excellent! (2,765 reviews)
"great location and great dining options"

Reviewed on 1 Aug 2026

Paradise Point Resort & Spa
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
The price is Rp4.127.038 per night from 5 Aug to 6 Aug
Rp4.127.038
Rp5.767.113 total
5 Aug - 6 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy 6 restaurants, 3 bars/lounges and breakfast (surcharge). Our guests praise the pool and the helpful ...
Manchester Grand Hyatt San Diego
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
The price is Rp2.903.344 per night from 2 Aug to 3 Aug
Rp2.903.344
Rp3.993.448 total
2 Aug - 3 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free Wi-Fi, 3 restaurants and breakfast (surcharge). Our guests praise the pool and the restaurant in ...
8.4/10 Very good! (6,275 reviews)
"It was ok but no kk"

Reviewed on 1 Aug 2026

Wyndham San Diego Bayside
Loews Coronado Bay Resort

Loews Coronado Bay Resort

4 out of 5
4000 Coronado Bay Rd Coronado CA
The price is Rp5.929.238 per night from 23 Aug to 24 Aug
Rp5.929.238
Rp7.491.926 total
23 Aug - 24 Aug
includes taxes & fees
Stay at this beach hotel in Coronado. Enjoy free Wi-Fi, 3 outdoor pools and a full-service spa. Our guests praise the pool and the helpful staff in their reviews. ...
9/10 Wonderful! (1,113 reviews)
"Our stay was wonderful for the most part. It’s in a secluded location that’s perfect for relaxing but the shuttle was convenient for transportation to other destinations."

Reviewed on 1 Aug 2026

Loews Coronado Bay Resort
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

2.5 out of 5
2485 Hotel Circle Place San Diego CA
The price is Rp2.865.498 per night from 31 Aug to 1 Sept
Rp2.865.498
Rp3.293.603 total
31 Aug - 1 Sept
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
8/10 Very good! (2,851 reviews)
"Good breakfast and clean room. Nice location to attractions."

Reviewed on 1 Aug 2026

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
The price is Rp3.766.598 per night from 1 Sept to 2 Sept
Rp3.766.598
Rp4.847.558 total
1 Sept - 2 Sept
includes taxes & fees
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina and 2 hot tubs. Our guests praise the pool and the restaurant in their reviews. Popular attractions ...
9/10 Wonderful! (4,411 reviews)
"My family and I always stay at The Dana we love that they do movie night by the pool and they are always so nice."

Reviewed on 1 Aug 2026

The Dana on Mission Bay
See all 4,953 properties in Otay Mesa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Otay Mesa

Find the best Otay Mesa areas for the activities you enjoy most.
A plaza with a traditional building, benches, and a large tree.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

A beach with surfers and swimmers during sunset.

Pacific Beach

The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Riviera Shores Beach while you're exploring the area.

A roller coaster under construction with scaffolding and a ticket booth in the foreground.

Mission Beach

If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.

A theater marquee with ornate designs and the name "Gaslamp Quarter".

Gaslamp Quarter

Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Nova SD – discover Gaslamp Quarter, a destination also famous for its shopping.

An aerial view of a coastal city with a marina, a large body of water, and a peninsula with buildings.

Mission Bay

If you're spending some time in Mission Bay, Mission Bay and Ski Beach are top sights worth seeing.

Otay Mesa Travel Guide