Otay Mesa Travel Guide
San Diego
Visit Otay Mesa
Stay near popular Otay Mesa attractions
Things to do
Tour of San Diego>Rosarito >Giant Christ>Puerto Nuevo Lobster
Taco Tuesday Hop to Tijuana from San Diego
From Tijuana: Valle de Guadalupe Shared Winery Tour
Crossing Borders: Tijuana Day Trip from San Diego
Top hotels in Otay Mesa
Paradise Point Resort & Spa
"Q"
Reviewed on 1 Aug 2026
Manchester Grand Hyatt San Diego
Wyndham San Diego Bayside
"Helpful front desk staff."
Reviewed on 31 Jul 2026
Loews Coronado Bay Resort
"Excelent highly recommend!"
Reviewed on 31 Jul 2026
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
"We regret to inform you that our recent stay resulted in bed bug bites sustained by my son and wife. We are profoundly disappointed by this experience and urge you to address this matter promptly. We kindly request that you ensure the suitability of the room for future guests. We are extremely ..."
Reviewed on 31 Jul 2026
The Dana on Mission Bay
Where to stay in Otay Mesa
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Pacific Beach
The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Riviera Shores Beach while you're exploring the area.
Mission Beach
If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.
Gaslamp Quarter
Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Nova SD – discover Gaslamp Quarter, a destination also famous for its shopping.
Mission Bay
If you're spending some time in Mission Bay, Mission Bay and Ski Beach are top sights worth seeing.
