Santa Ana Travel Guide

Panama City

A gazebo with columns, a large tree with hanging roots, and a building in the background.
A waterfront cityscape with numerous boats docked along the shore and a clear sky.

Stay near popular Santa Ana attractions

Things to do


Top hotels in Santa Ana

Casco View Apartments

Casco View Apartments

3.5 out of 5
C. 16 Oeste Panama City Provincia de Panamá
The price is Rp1.608.652 per night from 16 Jul to 17 Jul
Rp1.608.652
Rp2.312.247 total
16 Jul - 17 Jul
includes taxes & fees
Stay at this business-friendly condo in Panama City. Enjoy free Wi-Fi, breakfast (surcharge) and a 24-hour front desk. Popular attractions Albrook Shopping Mall ...
9/10 Wonderful! (100 reviews)
"Great layout with modern convenience for my family, sofa bed was generous and comfortable. Thoughtful kitchen tools made our stay easy."

Reviewed on 20 Jun 2026

Casco View Apartments
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
The price is Rp2.661.868 per night from 29 Jul to 30 Jul
Rp2.661.868
Rp2.928.055 total
29 Jul - 30 Jul
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and 3 restaurants. Our guests praise the breakfast and the pool in their reviews. ...
9/10 Wonderful! (5,738 reviews)
"My 23rd Floor had water damage and smelled like mildew."

Reviewed on 15 Jul 2026

Hotel Riu Plaza Panama
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
The price is Rp1.992.362 per night from 11 Aug to 12 Aug
Rp1.992.362
Rp2.191.544 total
11 Aug - 12 Aug
includes taxes & fees
Stay at this family-friendly hotel in Tocumen. Enjoy free Wi-Fi, breakfast (surcharge) and a free airport shuttle. Our guests praise the breakfast and the pool ...
8.6/10 Excellent! (2,633 reviews)
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Reviewed on 14 Jul 2026

Crowne Plaza Panama Airport by IHG
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa Panama City
The price is Rp2.686.591 per night from 3 Aug to 4 Aug
Rp2.686.591
Rp2.955.250 total
3 Aug - 4 Aug
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in their reviews. ...
8.4/10 Very good! (1,598 reviews)
"Rooms were immaculate, breakfast was great every morning. Cleaning was strange. I place my bag in the closet and the maid cleaned that out. I put in the closet to be safe, it WAS NOT."

Reviewed on 14 Jul 2026

Megapolis Hotel Panamá
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz Veracruz Panama
The price is Rp5.770.848 per night from 26 Jul to 27 Jul
Rp5.770.848
Rp5.770.848 total
26 Jul - 27 Jul
includes taxes & fees
Stay at this beach resort in Veracruz. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the pool and the helpful staff in their reviews. ...
7.6/10 Good! (1,023 reviews)
"We absolutely loved it. We stayed in the junior suite and it was amazing! The food was good and tasty! And the wildlife was interesting sloths, iguanas, and raccoons. We definitely plan to come back really soon!"

Reviewed on 15 Jul 2026

Dreams Playa Bonita Panama - All Inclusive
Principe Hotel and Suites

Principe Hotel and Suites

3 out of 5
Via Argentina Panama City Panama
The price is Rp1.025.760 per night from 16 Jul to 17 Jul
Rp1.025.760
Rp1.128.336 total
16 Jul - 17 Jul
includes taxes & fees
Stay at this business-friendly hotel in Panama City. Enjoy free Wi-Fi, free parking and room service. Our guests praise the helpful staff and the clean rooms ...
9/10 Wonderful! (1,960 reviews)
"Our stay at the Principe hotel was a great 5 night stay,the room was clean, spacious,relaxing and the AC was cooling great. The hotel is in a great location, everything in walking distance (restaurants,bars, convenient stores to buy snacks). We will definitely booked a room at the Principe hotel ..."

Reviewed on 15 Jul 2026

Principe Hotel and Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

Calidonia

Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Estación Lotería or Santo Tomas Station to explore sights like Via Espana.



Santa Ana Travel Guide