Santa Ana Travel Guide

Panama City

A gazebo with columns, a large tree with hanging roots, and a building in the background.
A waterfront cityscape with numerous boats docked along the shore and a clear sky.

Stay near popular Santa Ana attractions

El Machetazo Santa Ana

You can browse for the perfect souvenirs at El Machetazo Santa Ana during your visit to Panama City. Amble around the area's parks or visit its shops.
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Top hotels in Santa Ana

Casco View Apartments

Casco View Apartments

3.5 out of 5
C. 16 Oeste Panama City Provincia de Panamá
The price is Rp1.606.340 per night from 15 Jul to 16 Jul
Rp1.606.340
Rp2.308.924 total
15 Jul - 16 Jul
includes taxes & fees
Stay at this business-friendly condo in Panama City. Enjoy free Wi-Fi, breakfast (surcharge) and a 24-hour front desk. Popular attractions Albrook Shopping Mall ...
9/10 Wonderful! (100 reviews)
"Great layout with modern convenience for my family, sofa bed was generous and comfortable. Thoughtful kitchen tools made our stay easy."

Reviewed on 20 Jun 2026

Casco View Apartments
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
The price is Rp2.800.207 per night from 26 Jul to 27 Jul
Rp2.800.207
Rp3.080.228 total
26 Jul - 27 Jul
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and 3 restaurants. Our guests praise the breakfast and the pool in their reviews. ...
9/10 Wonderful! (5,724 reviews)
"Hotel was amazing especially for the price, located in a great spot."

Reviewed on 11 Jul 2026

Hotel Riu Plaza Panama
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
The price is Rp2.056.881 per night from 27 Jul to 28 Jul
Rp2.056.881
Rp2.262.641 total
27 Jul - 28 Jul
includes taxes & fees
Stay at this family-friendly hotel in Tocumen. Enjoy free Wi-Fi, breakfast (surcharge) and a free airport shuttle. Our guests praise the breakfast and the pool ...
8.6/10 Excellent! (2,626 reviews)
"Everything perfectly…..!"

Reviewed on 11 Jul 2026

Crowne Plaza Panama Airport by IHG
Principe Hotel and Suites

Principe Hotel and Suites

3 out of 5
Via Argentina Panama City Panama
Fully refundableReserve now, pay when you stay
The price is Rp1.024.286 per night from 14 Jul to 15 Jul
Rp1.024.286
Rp1.126.714 total
14 Jul - 15 Jul
includes taxes & fees
Stay at this business-friendly hotel in Panama City. Enjoy free Wi-Fi, free parking and room service. Our guests praise the helpful staff and the clean rooms ...
9/10 Wonderful! (1,950 reviews)
"Excelente ubicación para ir a todos lados con el metro"

Reviewed on 12 Jul 2026

Principe Hotel and Suites
Waldorf Astoria Panama

Waldorf Astoria Panama

5 out of 5
47th St. & Uruguay Street Panama City Panama
The price is Rp4.969.320 per night from 1 Aug to 2 Aug
Rp4.969.320
Rp5.466.252 total
1 Aug - 2 Aug
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy free Wi-Fi, a full-service spa and 2 restaurants. Our guests praise the helpful staff in their reviews. Popular ...
9/10 Wonderful! (1,001 reviews)
"Convenient location and a wonderful staff. Very friendly and helpful. The hotel is modern with good amenities."

Reviewed on 8 Jul 2026

Waldorf Astoria Panama
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz Veracruz Panama
The price is Rp5.762.554 per night from 18 Jul to 19 Jul
Rp5.762.554
Rp5.762.554 total
18 Jul - 19 Jul
includes taxes & fees
Stay at this beach resort in Veracruz. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the pool and the helpful staff in their reviews. ...
7.6/10 Good! (1,032 reviews)
"recomendable 100 x 100"

Reviewed on 10 Jul 2026

Dreams Playa Bonita Panama - All Inclusive
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.
A coastal cityscape with buildings, a hill with a church, and a clear blue sky.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

A spiraling skyscraper against a clear blue sky.
Photo by My World
Open Photo by My World

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

A city skyline with modern high-rise buildings and a river in the foreground.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

A bridge over a body of water with several boats.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

A coastal cityscape with high-rise buildings, a calm sea, and a rocky shoreline.

Calidonia

Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Estación Lotería or Santo Tomas Station to explore sights like Via Espana.

Santa Ana Travel Guide