Santa Ana Travel Guide

Panama City

A gazebo with columns, a large tree with hanging roots, and a building in the background.
A waterfront cityscape with numerous boats docked along the shore and a clear sky.

Stay near popular Santa Ana attractions

Things to do


Top hotels in Santa Ana

Casco View Apartments

Casco View Apartments

3.5 out of 5
C. 16 Oeste Panama City Provincia de Panamá
The price is Rp1.597.270 per night from 15 Jul to 16 Jul
Rp1.597.270
Rp2.295.887 total
15 Jul - 16 Jul
includes taxes & fees
Stay at this business-friendly condo in Panama City. Enjoy free Wi-Fi, breakfast (surcharge) and a 24-hour front desk. Popular attractions Albrook Shopping Mall ...
9/10 Wonderful! (100 reviews)
"Great layout with modern convenience for my family, sofa bed was generous and comfortable. Thoughtful kitchen tools made our stay easy."

Reviewed on 20 Jun 2026

Casco View Apartments
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
The price is Rp2.784.396 per night from 26 Jul to 27 Jul
Rp2.784.396
Rp3.062.836 total
26 Jul - 27 Jul
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and 3 restaurants. Our guests praise the breakfast and the pool in their reviews. ...
9/10 Wonderful! (5,680 reviews)
"Needs a bigger pool"

Reviewed on 3 Jul 2026

Hotel Riu Plaza Panama
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
The price is Rp2.407.042 per night from 20 Jul to 21 Jul
Rp2.407.042
Rp2.766.302 total
20 Jul - 21 Jul
includes taxes & fees
Stay at this family-friendly hotel in Tocumen. Enjoy free Wi-Fi, breakfast (surcharge) and a free airport shuttle. Our guests praise the breakfast and the pool ...
8.6/10 Excellent! (2,602 reviews)
"Esta bien para una noche de estadia para tomar vuelo al dia siguiente, el costos es alto para los servicios que ofrece"

Reviewed on 3 Jul 2026

Crowne Plaza Panama Airport by IHG
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz Veracruz Panama
The price is Rp5.730.017 per night from 11 Jul to 12 Jul
Rp5.730.017
Rp5.730.017 total
11 Jul - 12 Jul
includes taxes & fees
Stay at this beach resort in Veracruz. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the pool and the helpful staff in their reviews. ...
7.6/10 Good! (1,021 reviews)
"The restaurant staff were friendly and accommodating. I had an issue with concierge service. We were celebrating my wife’s birthday, so I requested to have the door decorated along with a small cake wishing her a happy birthday which is pretty standard for birthdays and anniversaries. I made the ..."

Reviewed on 3 Jul 2026

Dreams Playa Bonita Panama - All Inclusive
Principe Hotel and Suites

Principe Hotel and Suites

3 out of 5
Via Argentina Panama City Panama
The price is Rp1.018.502 per night from 6 Jul to 7 Jul
Rp1.018.502
Rp1.120.352 total
6 Jul - 7 Jul
includes taxes & fees
Stay at this business-friendly hotel in Panama City. Enjoy free Wi-Fi, free parking and room service. Our guests praise the helpful staff and the clean rooms ...
9/10 Wonderful! (1,922 reviews)
"This is a great hotel in the middle of the city. Cheap price. And great place to rest and clean up. No on site restaurant or snacks though. Right next door is a 24 hour deli, market, coffee and beer wine alcohol. Plenty of restaurant in the neighborhood."

Reviewed on 4 Jul 2026

Principe Hotel and Suites
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Plaza de la Independencia Casco Viejo Panama City Panama
The price is Rp3.134.364 per night from 28 Jul to 29 Jul
Rp3.134.364
Rp3.447.818 total
28 Jul - 29 Jul
includes taxes & fees
Stay at this spa hotel in Panama City. Enjoy free Wi-Fi, a full-service spa and 3 restaurants. Our guests praise the helpful staff and the clean rooms in their ...
9.2/10 Wonderful! (1,003 reviews)
"Beautiful hotel with great history! The location in Casco Viejo was perfect for our visit to Panama City and we were easily able to walk or order a car/Uber from there for various trips. We had a family suite, which was a king and full size bed room that worked well for our family of 3. The rooftop ..."

Reviewed on 30 Jun 2026

Central Hotel Panama Casco Viejo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

Calidonia

Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Estación Lotería or Santo Tomas Station to explore sights like Via Espana.



Santa Ana Travel Guide