Santa Ana Travel Guide

Panama City

Photo by Isa

Popular places to visit

Things to do


Top hotels in Santa Ana

Casco View Apartments

Casco View Apartments

3.5 out of 5
C. 16 Oeste Panama City Provincia de Panamá
Stay at this condo in Panama City. Enjoy free Wi-Fi, a 24-hour front desk and a garden. Popular attractions Albrook Shopping Mall and Cinta Costera are located ...
9.2/10 Wonderful! (50 reviews)
Room was clean large and great to have kitchen and laundry in the unit. The pool is small and not really a lounging area. Overall it was super loud, dogs barking, alarms going off and immediate area a little sketch

Reviewed on 27 Oct 2025

Casco View Apartments
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
The price is Rp1.908.249 per night from 2 Dec to 3 Dec
Rp1.908.249
Rp2.099.074 total
2 Dec - 3 Dec
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and 3 restaurants. Our guests praise the breakfast and the pool in their reviews. ...
9/10 Wonderful! (4,591 reviews)
Todo muy bien, buena ubicado, limpieza y muy buena atencion, buen desayuno, solo los tragos preparados de la piscina de poca calidad. Gracias por todos los dias maravillosos.

Reviewed on 27 Nov 2025

Hotel Riu Plaza Panama
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
The price is Rp1.787.560 per night from 8 Dec to 9 Dec
Rp1.787.560
Rp2.241.454 total
8 Dec - 9 Dec
includes taxes & fees
Stay at this family-friendly hotel in Tocumen. Enjoy free Wi-Fi, breakfast (surcharge) and a free airport shuttle. Our guests praise the breakfast and the pool ...
8.4/10 Very Good! (2,298 reviews)
Llegué tarde en la noche y me fui temprano. No pude disfrutar de ningún amenities.

Reviewed on 25 Nov 2025

Crowne Plaza Panama Airport by IHG
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
The price is Rp2.548.107 per night from 17 Dec to 18 Dec
Rp2.548.107
Rp2.802.901 total
17 Dec - 18 Dec
includes taxes & fees
Stay at this spa hotel in Panama City. Enjoy free Wi-Fi, a full-service spa and breakfast (surcharge). Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,023 reviews)
Room price is reasonable, location is good!

Reviewed on 24 Nov 2025

Las Americas Golden Tower Panama
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
The price is Rp2.126.062 per night from 5 Dec to 6 Dec
Rp2.126.062
Rp2.338.668 total
5 Dec - 6 Dec
includes taxes & fees
Stay at this 4-star spa resort in Panama City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.4/10 Very Good! (980 reviews)
Excelente atención y servicio La cuna de bebé era de material como fierro, insegura para bebés que ya se paran un poco El área de juegos de niños siempre mojada y no tenía protección solar podría adecuarse mejor

Reviewed on 1 Nov 2025

Sheraton Grand Panama
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa Panama City
The price is Rp2.151.384 per night from 21 Dec to 22 Dec
Rp2.151.384
Rp2.366.522 total
21 Dec - 22 Dec
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in their reviews. ...
8.4/10 Very Good! (1,236 reviews)
Every thing was perfect. Great hotel..! recommended 100%

Reviewed on 1 Dec 2025

Megapolis Hotel Panamá
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Santa Ana

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Casco Viejo

3.5/5(3 area reviews)

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Casco Viejo
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San Felipe

While visiting San Felipe, you might make a stop by sights like Independence Square and Interoceanic Canal Museum.

San Felipe
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El Chorrillo

While El Chorrillo isn't home to many top sights, Albrook Shopping Mall and Ancon Hill are some notable places to visit nearby.

El Chorrillo
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Calidonia

Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Estación Lotería or Santo Tomas Station to explore sights like Cinta Costera.

Calidonia
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Balboa

The restaurants and shopping are just a few features travellers like about Balboa. If you want to do some sightseeing nearby, Albrook Shopping Mall and Ancon Hill are a few top places to visit.

Balboa
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Marbella

You'll enjoy the restaurants and parks in Marbella. You might want to make time for a stop at Avenida Balboa or Cinta Costera.

Marbella


Santa Ana Travel Guide